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SGO2 shugoshin 2 [ Homo sapiens (human) ]

Gene ID: 151246, updated on 7-Jun-2020

Summary

Official Symbol
SGO2provided by HGNC
Official Full Name
shugoshin 2provided by HGNC
Primary source
HGNC:HGNC:30812
See related
Ensembl:ENSG00000163535 MIM:612425
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGOL2; TRIPIN
Expression
Biased expression in testis (RPKM 14.8), lymph node (RPKM 3.1) and 10 other tissues See more
Orthologs

Genomic context

See SGO2 in Genome Data Viewer
Location:
2q33.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (200510198..200584096)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (201390865..201448818)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated serine rich 2 like Neighboring gene uncharacterized LOC101927741 Neighboring gene potassium channel tetramerization domain containing 18 Neighboring gene aldehyde oxidase 1 Neighboring gene AOX3P-AOX2P readthrough, transcribed pseudogene Neighboring gene long intergenic non-protein coding RNA 1792 Neighboring gene aldehyde oxidase 3, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25211, MGC129665

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell division IEA
Inferred from Electronic Annotation
more info
 
homologous chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
meiotic sister chromatid cohesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
meiotic sister chromatid cohesion, centromeric IEA
Inferred from Electronic Annotation
more info
 
mitotic sister chromatid segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
chromosome, centromeric region IDA
Inferred from Direct Assay
more info
PubMed 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
condensed nuclear chromosome, centromeric region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cohesin complex IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
shugoshin 2
Names
shugoshin-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160033.1NP_001153505.1  shugoshin 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC012459, AC080164, AK302457, DB369428
    UniProtKB/TrEMBL
    B7Z7S9
  2. NM_001160046.1NP_001153518.1  shugoshin 2 isoform 3

    See identical proteins and their annotated locations for NP_001153518.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC012459, AC080164, AK095291
    UniProtKB/Swiss-Prot
    Q562F6
  3. NM_152524.6NP_689737.4  shugoshin 2 isoform 1

    See identical proteins and their annotated locations for NP_689737.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC012459, AC080164, BC092412, DB369428
    Consensus CDS
    CCDS42796.1
    UniProtKB/Swiss-Prot
    Q562F6
    Related
    ENSP00000350447.4, ENST00000357799.9

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    200510198..200584096
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003453.1XP_016858942.1  shugoshin 2 isoform X1

  2. XM_017003454.2XP_016858943.1  shugoshin 2 isoform X2

  3. XM_017003452.2XP_016858941.1  shugoshin 2 isoform X1

  4. XM_005246345.4XP_005246402.1  shugoshin 2 isoform X4

    See identical proteins and their annotated locations for XP_005246402.1

    UniProtKB/Swiss-Prot
    Q562F6
  5. XM_005246344.4XP_005246401.2  shugoshin 2 isoform X3

  6. XM_011510734.3XP_011509036.1  shugoshin 2 isoform X4

    See identical proteins and their annotated locations for XP_011509036.1

    UniProtKB/Swiss-Prot
    Q562F6
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