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Has2 hyaluronan synthase 2 [ Mus musculus (house mouse) ]

Gene ID: 15117, updated on 23-May-2018
Official Symbol
Has2provided by MGI
Official Full Name
hyaluronan synthase 2provided by MGI
Primary source
MGI:MGI:107821
See related
Ensembl:ENSMUSG00000022367 Vega:OTTMUSG00000036745
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in limb E14.5 (RPKM 5.1), CNS E11.5 (RPKM 2.1) and 7 other tissues See more
Orthologs
See Has2 in Genome Data Viewer
Location:
15 D1; 15 23.31 cM
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (56665627..56694546, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (56497182..56526101, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene hemoglobin alpha, pseudogene 3 Neighboring gene predicted gene, 41326 Neighboring gene hyaluronan synthase 2, opposite strand Neighboring gene predicted gene, 41327 Neighboring gene predicted gene, 38516 Neighboring gene predicted gene 5673

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hyaluronan synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hyaluronan synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
hyaluronan synthase activity ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring glycosyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
atrioventricular canal development IMP
Inferred from Mutant Phenotype
more info
PubMed 
bone morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to platelet-derived growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
endocardial cushion to mesenchymal transition IMP
Inferred from Mutant Phenotype
more info
PubMed 
extracellular matrix assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular matrix assembly IDA
Inferred from Direct Assay
more info
PubMed 
extracellular polysaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular polysaccharide biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
hyaluronan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hyaluronan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
hyaluronan biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
hyaluronan metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of hyaluronan biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of keratinocyte migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of keratinocyte proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of monocyte aggregation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of smooth muscle cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of substrate adhesion-dependent cell spreading ISO
Inferred from Sequence Orthology
more info
 
regulation of extracellular matrix assembly ISO
Inferred from Sequence Orthology
more info
 
vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
hyaluronan synthase 2
Names
HA synthase 2
hyaluronan synthase homolog
hyaluronate synthase 2
hyaluronic acid synthase 2
NP_032242.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008216.3NP_032242.3  hyaluronan synthase 2

    See identical proteins and their annotated locations for NP_032242.3

    Status: VALIDATED

    Source sequence(s)
    BC080281, BY110777
    Consensus CDS
    CCDS27480.1
    UniProtKB/Swiss-Prot
    P70312
    Related
    ENSMUSP00000062212.7, OTTMUSP00000052379, ENSMUST00000050544.7, OTTMUST00000094254
    Conserved Domains (1) summary
    cd06434
    Location:84361
    GT2_HAS; Hyaluronan synthases catalyze polymerization of hyaluronan

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    56665627..56694546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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