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Has1 hyaluronan synthase 1 [ Mus musculus (house mouse) ]

Gene ID: 15116, updated on 23-May-2018
Official Symbol
Has1provided by MGI
Official Full Name
hyaluronan synthase 1provided by MGI
Primary source
MGI:MGI:106590
See related
Ensembl:ENSMUSG00000003665
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HAS
Expression
Broad expression in ovary adult (RPKM 1.3), lung adult (RPKM 1.2) and 23 other tissues See more
Orthologs
See Has1 in Genome Data Viewer
Location:
17 A3.2; 17 10.53 cM
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (17843326..17856194, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (17980290..17992152, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene sperm acrosome associated 6 Neighboring gene microRNA let7e Neighboring gene microRNA 125a Neighboring gene predicted gene, 36907 Neighboring gene formyl peptide receptor 1 Neighboring gene formyl peptide receptor 2

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Clone Names

  • MGC159127, MGC159129

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hyaluronan synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hyaluronan synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring glycosyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to platelet-derived growth factor stimulus ISO
Inferred from Sequence Orthology
more info
 
extracellular matrix assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular matrix assembly IDA
Inferred from Direct Assay
more info
PubMed 
extracellular polysaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular polysaccharide biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
hyaluronan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hyaluronan biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of fibroblast migration ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
hyaluronan synthase 1
Names
HA synthase 1
hyaluronan synthase1
hyaluronate synthase 1
hyaluronic acid synthase 1
NP_032241.1
XP_011244611.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008215.2NP_032241.1  hyaluronan synthase 1

    See identical proteins and their annotated locations for NP_032241.1

    Status: VALIDATED

    Source sequence(s)
    AK138203, AW488161, D82964
    Consensus CDS
    CCDS37459.1
    UniProtKB/Swiss-Prot
    Q61647
    UniProtKB/TrEMBL
    Q3UUP6
    Related
    ENSMUSP00000003762.6, ENSMUST00000003762.6
    Conserved Domains (2) summary
    TIGR04242
    Location:51493
    nodulat_NodC; chitooligosaccharide synthase NodC
    cl11394
    Location:100391
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    17843326..17856194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246309.2XP_011244611.1  hyaluronan synthase 1 isoform X1

    Conserved Domains (2) summary
    TIGR04242
    Location:57499
    nodulat_NodC; chitooligosaccharide synthase NodC
    cl11394
    Location:106397
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
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