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ZNF385B zinc finger protein 385B [ Homo sapiens (human) ]

Gene ID: 151126, updated on 12-Oct-2019

Summary

Official Symbol
ZNF385Bprovided by HGNC
Official Full Name
zinc finger protein 385Bprovided by HGNC
Primary source
HGNC:HGNC:26332
See related
Ensembl:ENSG00000144331 MIM:612344
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF533
Expression
Broad expression in lung (RPKM 1.7), heart (RPKM 1.4) and 14 other tissues See more
Orthologs

Genomic context

See ZNF385B in Genome Data Viewer
Location:
2q31.2-q31.3
Exon count:
25
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (179441982..179864550, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (180306709..180726232, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene SEC14 and spectrin domain containing 1 Neighboring gene RAD52 pseudogene 1 Neighboring gene uncharacterized LOC101927073 Neighboring gene uncharacterized LOC107985967 Neighboring gene TXNL4A pseudogene 1 Neighboring gene microRNA 1258 Neighboring gene CWC22 spliceosome associated protein homolog Neighboring gene uncharacterized LOC105373767

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25270

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
p53 binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
intrinsic apoptotic signaling pathway by p53 class mediator IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 385B
Names
zinc finger protein 533

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113397.2NP_001106868.1  zinc finger protein 385B isoform 2

    See identical proteins and their annotated locations for NP_001106868.1

    Status: VALIDATED

    Source sequence(s)
    AC062033, AK096822, BC033042, BC092423
    Consensus CDS
    CCDS46463.1
    UniProtKB/Swiss-Prot
    Q569K4
    Related
    ENSP00000386379.1, ENST00000409343.5
    Conserved Domains (2) summary
    sd00020
    Location:211273
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:273296
    zf-met; Zinc-finger of C2H2 type
  2. NM_001113398.3NP_001106869.1  zinc finger protein 385B isoform 3

    See identical proteins and their annotated locations for NP_001106869.1

    Status: VALIDATED

    Source sequence(s)
    AK057999, BC033042, BC092423
    Consensus CDS
    CCDS46464.1
    UniProtKB/Swiss-Prot
    Q569K4
    Related
    ENSP00000338225.5, ENST00000336917.9
    Conserved Domains (2) summary
    sd00020
    Location:185247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:246270
    zf-met; Zinc-finger of C2H2 type
  3. NM_001282725.2NP_001269654.1  zinc finger protein 385B isoform 3

    See identical proteins and their annotated locations for NP_001269654.1

    Status: VALIDATED

    Source sequence(s)
    BC033042, BC038422, BC048123, BC092423
    Consensus CDS
    CCDS46464.1
    UniProtKB/Swiss-Prot
    Q569K4
    Related
    ENSP00000386507.1, ENST00000409692.5
    Conserved Domains (2) summary
    sd00020
    Location:185247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:246270
    zf-met; Zinc-finger of C2H2 type
  4. NM_001352808.2NP_001339737.1  zinc finger protein 385B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
    Consensus CDS
    CCDS33339.2
    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:302364
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:363387
    zf-met; Zinc-finger of C2H2 type
  5. NM_001352809.2NP_001339738.1  zinc finger protein 385B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC092642, AC093604, BC092423
    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:348410
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:409433
    zf-met; Zinc-finger of C2H2 type
  6. NM_001352810.2NP_001339739.1  zinc finger protein 385B isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:329391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:390414
    zf-met; Zinc-finger of C2H2 type
  7. NM_001352811.2NP_001339740.1  zinc finger protein 385B isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:315377
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:376400
    zf-met; Zinc-finger of C2H2 type
  8. NM_001352812.2NP_001339741.1  zinc finger protein 385B isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC093604, BC092423
    Conserved Domains (2) summary
    sd00020
    Location:219281
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:280304
    zf-met; Zinc-finger of C2H2 type
  9. NM_001352813.1NP_001339742.1  zinc finger protein 385B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC093604, BC092423
    Consensus CDS
    CCDS46464.1
    Conserved Domains (2) summary
    sd00020
    Location:185247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:246270
    zf-met; Zinc-finger of C2H2 type
  10. NM_001352814.2NP_001339743.1  zinc finger protein 385B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC093604, BC092423
    Consensus CDS
    CCDS46464.1
    Conserved Domains (2) summary
    sd00020
    Location:185247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:246270
    zf-met; Zinc-finger of C2H2 type
  11. NM_001352815.1NP_001339744.1  zinc finger protein 385B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC093604, BC092423
    Consensus CDS
    CCDS46464.1
    Conserved Domains (2) summary
    sd00020
    Location:185247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:246270
    zf-met; Zinc-finger of C2H2 type
  12. NM_001352816.2NP_001339745.1  zinc finger protein 385B isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, BC092423
    Conserved Domains (2) summary
    sd00020
    Location:173235
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:234258
    zf-met; Zinc-finger of C2H2 type
  13. NM_001352817.1NP_001339746.1  zinc finger protein 385B isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, BC092423
    Conserved Domains (2) summary
    sd00020
    Location:155217
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:216240
    zf-met; Zinc-finger of C2H2 type
  14. NM_152520.6NP_689733.4  zinc finger protein 385B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
    Consensus CDS
    CCDS33339.2
    Related
    ENSP00000386845.2, ENST00000410066.7
    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:302364
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:363387
    zf-met; Zinc-finger of C2H2 type

RNA

  1. NR_104234.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BC048123
    Related
    ENST00000466398.5
  2. NR_148054.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
  3. NR_148055.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, AC093604, BC092423
  4. NR_148056.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
  5. NR_148057.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, BC092423
  6. NR_148058.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC068042, AC092642, AC093604, BC092423
  7. NR_148059.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC062033, AC068042, BC092423

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    179441982..179864550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510713.3XP_011509015.1  zinc finger protein 385B isoform X1

    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:342404
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:404427
    zf-met; Zinc-finger of C2H2 type
  2. XM_011510717.2XP_011509019.1  zinc finger protein 385B isoform X2

    See identical proteins and their annotated locations for XP_011509019.1

    Conserved Domains (2) summary
    sd00020
    Location:245307
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:307330
    zf-met; Zinc-finger of C2H2 type
  3. XM_011510716.2XP_011509018.1  zinc finger protein 385B isoform X2

    See identical proteins and their annotated locations for XP_011509018.1

    Conserved Domains (2) summary
    sd00020
    Location:245307
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:307330
    zf-met; Zinc-finger of C2H2 type
  4. XM_011510720.2XP_011509022.1  zinc finger protein 385B isoform X3

    See identical proteins and their annotated locations for XP_011509022.1

    Conserved Domains (2) summary
    sd00020
    Location:225287
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:287310
    zf-met; Zinc-finger of C2H2 type
  5. XM_011510719.2XP_011509021.1  zinc finger protein 385B isoform X3

    See identical proteins and their annotated locations for XP_011509021.1

    Conserved Domains (2) summary
    sd00020
    Location:225287
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:287310
    zf-met; Zinc-finger of C2H2 type
  6. XM_011510721.3XP_011509023.1  zinc finger protein 385B isoform X4

    Conserved Domains (2) summary
    sd00020
    Location:212274
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:274297
    zf-met; Zinc-finger of C2H2 type
  7. XM_011510723.2XP_011509025.1  zinc finger protein 385B isoform X5

    Conserved Domains (3) summary
    smart00451
    Location:5080
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:187209
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12874
    Location:187209
    zf-met; Zinc-finger of C2H2 type
  8. XM_017003441.2XP_016858930.1  zinc finger protein 385B isoform X6

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