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KANSL1L KAT8 regulatory NSL complex subunit 1 like [ Homo sapiens (human) ]

Gene ID: 151050, updated on 5-Aug-2022

Summary

Official Symbol
KANSL1Lprovided by HGNC
Official Full Name
KAT8 regulatory NSL complex subunit 1 likeprovided by HGNC
Primary source
HGNC:HGNC:26310
See related
Ensembl:ENSG00000144445 MIM:613833; AllianceGenome:HGNC:26310
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MSL1v2; C2orf67
Summary
Predicted to enable histone acetyltransferase binding activity. Predicted to be part of NSL complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis (RPKM 5.3), ovary (RPKM 4.5) and 25 other tissues See more
Orthologs
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Genomic context

See KANSL1L in Genome Data Viewer
Location:
2q34
Exon count:
24
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (210021421..210172760, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (210502126..210652110, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (210886145..211036133, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene unc-80 homolog, NALCN channel complex subunit Neighboring gene Sharpr-MPRA regulatory region 8450 Neighboring gene Sharpr-MPRA regulatory region 8902 Neighboring gene KANSL1L antisense RNA 1 Neighboring gene ribulose-5-phosphate-3-epimerase Neighboring gene ribosomal protein L6 pseudogene 6 Neighboring gene uncharacterized LOC107985977 Neighboring gene uncharacterized LOC124907972 Neighboring gene acyl-CoA dehydrogenase long chain

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23861

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables histone acetyltransferase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of NSL complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
KAT8 regulatory NSL complex subunit 1-like protein
Names
KIAA1267-like
male-specific lethal 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001307976.2NP_001294905.1  KAT8 regulatory NSL complex subunit 1-like protein isoform 2

    See identical proteins and their annotated locations for NP_001294905.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
    Source sequence(s)
    AA252480, AA404520, AC006994, AI289109, AK308432, BC143914, BU568066, DR002867
    Consensus CDS
    CCDS77519.1
    UniProtKB/Swiss-Prot
    A0AUZ9
    Related
    ENSP00000405724.1, ENST00000418791.5
    Conserved Domains (1) summary
    pfam15275
    Location:754873
    PEHE; PEHE domain
  2. NM_152519.4NP_689732.2  KAT8 regulatory NSL complex subunit 1-like protein isoform 1

    See identical proteins and their annotated locations for NP_689732.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC006994, AI289109, AK074441, AL133053, BC032837, BQ948513, BU568066, CA393360, DR002867
    Consensus CDS
    CCDS33370.1
    UniProtKB/Swiss-Prot
    A0AUZ9, Q9UFC3
    Related
    ENSP00000281772.8, ENST00000281772.14
    Conserved Domains (1) summary
    pfam15275
    Location:796915
    PEHE; PEHE domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    210021421..210172760 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047443489.1XP_047299445.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X2

  2. XM_005246330.4XP_005246387.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_005246387.1

    UniProtKB/Swiss-Prot
    A0AUZ9, Q9UFC3
    Conserved Domains (1) summary
    pfam15275
    Location:796915
    PEHE; PEHE domain
  3. XM_011510706.4XP_011509008.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_011509008.1

    UniProtKB/Swiss-Prot
    A0AUZ9, Q9UFC3
    Conserved Domains (1) summary
    pfam15275
    Location:796915
    PEHE; PEHE domain
  4. XM_005246332.6XP_005246389.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X4

    Conserved Domains (1) summary
    pfam15275
    Location:787906
    PEHE; PEHE domain
  5. XM_005246328.5XP_005246385.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X1

    Conserved Domains (1) summary
    pfam15275
    Location:829948
    PEHE; PEHE domain
  6. XM_005246329.5XP_005246386.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    See identical proteins and their annotated locations for XP_005246386.1

    UniProtKB/Swiss-Prot
    A0AUZ9, Q9UFC3
    Conserved Domains (1) summary
    pfam15275
    Location:796915
    PEHE; PEHE domain
  7. XM_017003430.2XP_016858919.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X3

    UniProtKB/Swiss-Prot
    A0AUZ9, Q9UFC3
    Conserved Domains (1) summary
    pfam15275
    Location:796915
    PEHE; PEHE domain
  8. XM_011510710.3XP_011509012.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X8

    Conserved Domains (1) summary
    pfam15275
    Location:368487
    PEHE; PEHE domain
  9. XM_017003431.2XP_016858920.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X14

  10. XM_047443490.1XP_047299446.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X5

    Related
    ENSP00000393432.1, ENST00000457374.5
  11. XM_047443491.1XP_047299447.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X9

  12. XM_047443494.1XP_047299450.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X13

  13. XM_011510709.3XP_011509011.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X6

  14. XM_047443493.1XP_047299449.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X12

  15. XM_047443492.1XP_047299448.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X11

  16. XM_005246334.6XP_005246391.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X10

  17. XM_006712320.4XP_006712383.1  KAT8 regulatory NSL complex subunit 1-like protein isoform X7

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    210502126..210652110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)