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ITPRIPL1 ITPRIP like 1 [ Homo sapiens (human) ]

Gene ID: 150771, updated on 23-Nov-2021

Summary

Official Symbol
ITPRIPL1provided by HGNC
Official Full Name
ITPRIP like 1provided by HGNC
Primary source
HGNC:HGNC:29371
See related
Ensembl:ENSG00000198885
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KIAA1754L
Expression
Broad expression in testis (RPKM 4.7), lymph node (RPKM 1.3) and 15 other tissues See more
Orthologs
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Genomic context

See ITPRIPL1 in Genome Data Viewer
Location:
2q11.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (96325317..96330507)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (96991055..96996245)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein U5 subunit 200 Neighboring gene cytosolic iron-sulfur assembly component 1 Neighboring gene Sharpr-MPRA regulatory region 61 Neighboring gene non-SMC condensin I complex subunit H Neighboring gene neuralized E3 ubiquitin protein ligase 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
inositol 1,4,5-trisphosphate receptor-interacting protein-like 1
Names
inositol 1,4,5-triphosphate receptor-interacting protein-like 1
inositol 1,4,5-trisphosphate receptor interacting protein-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050731.1 RefSeqGene

    Range
    5001..8030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001008949.3NP_001008949.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 2

    See identical proteins and their annotated locations for NP_001008949.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' sequence, as compared to variant 1. The encoded isoform 2 has a distinct and shorter N-terminus, as compared to isoform 1.
    Source sequence(s)
    AC021188, BC073153, CN263466, R37132
    Consensus CDS
    CCDS46360.1
    UniProtKB/Swiss-Prot
    Q6GPH6
    Related
    ENSP00000389308.2, ENST00000439118.3
    Conserved Domains (1) summary
    pfam03281
    Location:356522
    Mab-21; Mab-21 protein
  2. NM_001163523.2NP_001156995.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001156995.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR and uses a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3, 4, and 5 all encode the same isoform (3).
    Source sequence(s)
    AC021188
    Consensus CDS
    CCDS54378.1
    UniProtKB/Swiss-Prot
    Q6GPH6
    Related
    ENSP00000439566.1, ENST00000536814.1
    Conserved Domains (1) summary
    pfam03281
    Location:348514
    Mab-21; Mab-21 protein
  3. NM_001163524.1NP_001156996.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001156996.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has an alternate 5' splice pattern and uses a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3, 4, and 5 all encode the same isoform (3).
    Source sequence(s)
    AC021188
    Consensus CDS
    CCDS54378.1
    UniProtKB/Swiss-Prot
    Q6GPH6
    Conserved Domains (1) summary
    pfam03281
    Location:348514
    Mab-21; Mab-21 protein
  4. NM_001324490.1NP_001311419.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 3 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) has an alternate 5' splice pattern and uses a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3, 4, and 5 all encode the same isoform (3).
    Source sequence(s)
    BC073153, BI829328, CD300165, R37132
    Consensus CDS
    CCDS54378.1
    UniProtKB/Swiss-Prot
    Q6GPH6
    Conserved Domains (1) summary
    pfam03281
    Location:348514
    Mab-21; Mab-21 protein
  5. NM_178495.6NP_848590.3  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC021188, BC034503, BC073153, BI829328, R37132
    Consensus CDS
    CCDS33250.1
    UniProtKB/Swiss-Prot
    Q6GPH6
    Related
    ENSP00000355121.4, ENST00000361124.5
    Conserved Domains (1) summary
    pfam03281
    Location:364530
    Mab-21; Mab-21 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    96325317..96330507
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017003427.1XP_016858916.1  inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 isoform X1

    UniProtKB/Swiss-Prot
    Q6GPH6
    Conserved Domains (1) summary
    pfam03281
    Location:356522
    Mab-21; Mab-21 protein
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