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C2orf15 chromosome 2 open reading frame 15 [ Homo sapiens (human) ]

Gene ID: 150590, updated on 26-Oct-2022

Summary

Official Symbol
C2orf15provided by HGNC
Official Full Name
chromosome 2 open reading frame 15provided by HGNC
Primary source
HGNC:HGNC:28436
See related
Ensembl:ENSG00000273045 AllianceGenome:HGNC:28436
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thyroid (RPKM 3.3), kidney (RPKM 2.5) and 23 other tissues See more
Orthologs
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Genomic context

See C2orf15 in Genome Data Viewer
Location:
2q11.2
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (99141707..99151669)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (99600577..99610540)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (99758170..99768132)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene CRACD like Neighboring gene Sharpr-MPRA regulatory region 6151 Neighboring gene testis specific 10 Neighboring gene SMC3 pseudogene 1 Neighboring gene lipoyltransferase 1 Neighboring gene microtubule interacting and trafficking domain containing 1 Neighboring gene mitochondrial ribosomal protein L30

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
uncharacterized protein C2orf15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001317992.2NP_001304921.2  uncharacterized protein C2orf15

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC092587
    Consensus CDS
    CCDS2038.2
    UniProtKB/Swiss-Prot
    Q8WU43
    UniProtKB/TrEMBL
    A0A3F2YNW3
    Related
    ENSP00000386654.2, ENST00000409684.2
    Conserved Domains (1) summary
    pfam17701
    Location:191
    DUF5547; Family of unknown function (DUF5547)
  2. NM_144706.4NP_653307.2  uncharacterized protein C2orf15

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC092587, BC021264
    Consensus CDS
    CCDS2038.2
    UniProtKB/Swiss-Prot
    Q8WU43
    UniProtKB/TrEMBL
    A0A3F2YNW3
    Related
    ENSP00000497775.2, ENST00000650052.2
    Conserved Domains (1) summary
    pfam17701
    Location:191
    DUF5547; Family of unknown function (DUF5547)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    99141707..99151669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    99600577..99610540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)