Format

Send to:

Choose Destination

XKR3 XK related 3 [ Homo sapiens (human) ]

Gene ID: 150165, updated on 5-Jan-2022

Summary

Official Symbol
XKR3provided by HGNC
Official Full Name
XK related 3provided by HGNC
Primary source
HGNC:HGNC:28778
See related
Ensembl:ENSG00000172967 MIM:611674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
XRG3; XTES
Summary
XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008]
Expression
Restricted expression toward testis (RPKM 3.4) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See XKR3 in Genome Data Viewer
Location:
22q11.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (16783480..16825411, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (17264370..17306301, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene von Willebrand factor pseudogene 1 Neighboring gene long intergenic non-protein coding RNA 1665 Neighboring gene HSFY1 pseudogene 1 Neighboring gene glycoprotein M6B pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC57211

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
XK-related protein 3
Names
X Kell blood group precursor-related family, member 3
X-linked Kx blood group related 3
XK, Kell blood group complex subunit-related family, member 3
expressed in testis
x Kell blood group-related 3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001318251.3NP_001305180.1  XK-related protein 3

    Status: VALIDATED

    Source sequence(s)
    AC005301, AC007064
    Consensus CDS
    CCDS42975.1
    UniProtKB/Swiss-Prot
    Q5GH77
    UniProtKB/TrEMBL
    B7ZMN2
    Conserved Domains (1) summary
    pfam09815
    Location:35402
    XK-related; XK-related protein
  2. NM_001386955.1NP_001373884.1  XK-related protein 3

    Status: VALIDATED

    Source sequence(s)
    AC005301, AC007064
    Related
    ENSP00000507478.1, ENST00000684488.1
    Conserved Domains (1) summary
    pfam09815
    Location:35402
    XK-related; XK-related protein
  3. NM_001386956.1NP_001373885.1  XK-related protein 3

    Status: VALIDATED

    Source sequence(s)
    AC005301, AC007064
    Conserved Domains (1) summary
    pfam09815
    Location:35402
    XK-related; XK-related protein
  4. NM_001386957.1NP_001373886.1  XK-related protein 3

    Status: VALIDATED

    Source sequence(s)
    AC005301, AC007064
    Conserved Domains (1) summary
    pfam09815
    Location:35402
    XK-related; XK-related protein
  5. NM_175878.5NP_787074.2  XK-related protein 3

    See identical proteins and their annotated locations for NP_787074.2

    Status: VALIDATED

    Source sequence(s)
    AC005301, AC007064
    Consensus CDS
    CCDS42975.1
    UniProtKB/Swiss-Prot
    Q5GH77
    Related
    ENSP00000331704.5, ENST00000331428.5
    Conserved Domains (1) summary
    pfam09815
    Location:35402
    XK-related; XK-related protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    16783480..16825411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center