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CCT8L2 chaperonin containing TCP1 subunit 8 like 2 [ Homo sapiens (human) ]

Gene ID: 150160, updated on 25-Nov-2021

Summary

Official Symbol
CCT8L2provided by HGNC
Official Full Name
chaperonin containing TCP1 subunit 8 like 2provided by HGNC
Primary source
HGNC:HGNC:15553
See related
Ensembl:ENSG00000198445
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CESK1
Orthologs
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Genomic context

See CCT8L2 in Genome Data Viewer
Location:
22q11.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (16590751..16592810, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (17071641..17073700, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha pseudogene Neighboring gene KCNMB3 pseudogene 1 Neighboring gene fatty acid binding protein 5 pseudogene 11 Neighboring gene TPTE pseudogene 1 Neighboring gene solute carrier family 25 member 15 pseudogene 5

Genomic regions, transcripts, and products

Phenotypes

Associated conditions

Description Tests
A possible mechanism behind autoimmune disorders discovered by genome-wide linkage and association analysis in celiac disease.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC118839, MGC118840

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables anion channel activity TAS
Traceable Author Statement
more info
 
enables calcium-activated potassium channel activity TAS
Traceable Author Statement
more info
 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in inorganic anion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of chaperonin-containing T-complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
T-complex protein 1 subunit theta-like 2
Names
chaperonin containing TCP1, subunit 8 (theta)-like 2
putative T-complex protein 1 subunit theta-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014406.5NP_055221.1  T-complex protein 1 subunit theta-like 2

    See identical proteins and their annotated locations for NP_055221.1

    Status: VALIDATED

    Source sequence(s)
    AP000547, BC022006, BC033797
    Consensus CDS
    CCDS13738.1
    UniProtKB/Swiss-Prot
    Q96SF2
    Related
    ENSP00000353048.3, ENST00000359963.4
    Conserved Domains (2) summary
    pfam00118
    Location:43524
    Cpn60_TCP1; TCP-1/cpn60 chaperonin family
    cl02777
    Location:32524
    chaperonin_like; chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    16590751..16592810 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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