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PAB_RS07200 threonine--tRNA ligase [ Pyrococcus abyssi GE5 ]

Gene ID: 1496731, discontinued on 14-Dec-2023
  • This record was discontinued.

Summary

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Gene symbol
PAB_RS07200
Gene description
threonine--tRNA ligase
Locus tag
PAB_RS07200
Gene type
protein coding
Organism
Pyrococcus abyssi GE5 (strain: Orsay, type-material: type strain of Pyrococcus abyssi)
Lineage
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PAB1490
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000868.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transition states. Trapping a transition state in a computationally designed protein bottle. Pearson AD, et al. Science, 2015 Feb 20. PMID 25700516, Free PMC Article
  2. Mechanistic insights into cognate substrate discrimination during proofreading in translation. Hussain T, et al. Proc Natl Acad Sci U S A, 2010 Dec 21. PMID 21098258, Free PMC Article
  3. Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea. Hussain T, et al. EMBO J, 2006 Sep 6. PMID 16902403, Free PMC Article
  4. A D-amino acid editing module coupled to the translational apparatus in archaea. Dwivedi S, et al. Nat Struct Mol Biol, 2005 Jun. PMID 15908961
  5. Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme. Ahmad S, et al. Nat Commun, 2015 Jun 26. PMID 26113036, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A single residue plays a pivotal role in the inversion of enantioselectivity both in Pab-NTD and DTD.
    Title: Post-transfer editing mechanism of a D-aminoacyl-tRNA deacylase-like domain in threonyl-tRNA synthetase from archaea.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
threonine--tRNA ligase
WP_010868458.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000868.1 Reference assembly

    Range
    1297117..1298994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010868458.1 threonine--tRNA ligase [Pyrococcus abyssi]

    See identical proteins and their annotated locations for WP_010868458.1

    Conserved Domains (4) summary
    PRK03991
    Location:1 → 624
    PRK03991; threonyl-tRNA synthetase; Validated
    cd00771
    Location:206 → 510
    ThrRS_core; Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent ...
    cd00860
    Location:510 → 600
    ThrRS_anticodon; ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is ...
    pfam08915
    Location:1 → 139
    tRNA-Thr_ED; Archaea-specific editing domain of threonyl-tRNA synthetase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9UZ14.1

Gene LinkOut

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