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GARIN4 golgi associated RAB2 interactor family member 4 [ Homo sapiens (human) ]

Gene ID: 149647, updated on 26-Nov-2021

Summary

Official Symbol
GARIN4provided by HGNC
Official Full Name
golgi associated RAB2 interactor family member 4provided by HGNC
Primary source
HGNC:HGNC:26541
See related
Ensembl:ENSG00000162771
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM71A; GARI-L4
Summary
This gene encodes a protein that interacts with the Rab2B small GTPase and may be important for integrity of the Golgi body. A knockdown of this gene induces fragmentation of the Golgi, similar to the effect seen with a knockdown of the Rab2B small GTPase. The encoded protein has an N-terminal Rab-binding domain specific for Rab2B. [provided by RefSeq, Feb 2017]
Orthologs
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Genomic context

See GARIN4 in Genome Data Viewer
Location:
1q32.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (212624474..212626775)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (212797816..212800117)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene activating transcription factor 3 Neighboring gene Sharpr-MPRA regulatory region 14467 Neighboring gene Sharpr-MPRA regulatory region 14805 Neighboring gene long intergenic non-protein coding RNA 2773 Neighboring gene riboflavin kinase pseudogene Neighboring gene Sharpr-MPRA regulatory region 1202

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ32796, FLJ40118

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus HDA PubMed 

General protein information

Preferred Names
protein FAM71A
Names
Golgi-associated Rab2B interactor-like 4
family with sequence similarity 71 member A
testis secretory sperm-binding protein Li 209a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053140.1 RefSeqGene

    Range
    5028..7329
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_153606.4NP_705834.2  protein FAM71A

    See identical proteins and their annotated locations for NP_705834.2

    Status: REVIEWED

    Source sequence(s)
    AK057358, AK301981, AK315021, DB031502, DB509538
    Consensus CDS
    CCDS1507.1
    UniProtKB/Swiss-Prot
    Q8IYT1
    UniProtKB/TrEMBL
    B2RCB4, B3KQ44, B4DXH7
    Related
    ENSP00000294829.3, ENST00000294829.5
    Conserved Domains (1) summary
    pfam12480
    Location:115184
    DUF3699; Protein of unknown function (DUF3699)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    212624474..212626775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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