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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001164883.2 → NP_001158355.1 catenin alpha-2 isoform 2
See identical proteins and their annotated locations for NP_001158355.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region but maintains the reading frame compared to variant 1. The resulting isoform (2) lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
AK295181, BC052996, DA313393
- Consensus CDS
-
CCDS54371.1
- UniProtKB/Swiss-Prot
-
P26232
- Related
- ENSP00000486160.1, ENST00000629316.2
- Conserved Domains (1) summary
-
- pfam01044
Location:81 → 821
- Vinculin; Vinculin family
-
NM_001282597.3 → NP_001269526.1 catenin alpha-2 isoform 3
See identical proteins and their annotated locations for NP_001269526.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
- Source sequence(s)
-
AC008067, AC010975, AC011741, AC011746, AC096573, AC096753, AC104780, FJ695201
- Consensus CDS
-
CCDS62944.1
- UniProtKB/Swiss-Prot
-
P26232
- Conserved Domains (1) summary
-
- pfam01044
Location:18 → 914
- Vinculin; Vinculin family
-
NM_001282598.2 → NP_001269527.1 catenin alpha-2 isoform 4
See identical proteins and their annotated locations for NP_001269527.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) has an alternate 5' terminal exon that includes an upstream in-frame AUG start codon, and lacks an in-frame exon in the 3' coding region, compared to variant 3. The resulting isoform (4) is longer at the N-terminus but lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
AC010975, AK303035, BC052996
- UniProtKB/Swiss-Prot
-
P26232
- Conserved Domains (1) summary
-
- pfam01044
Location:115 → 900
- Vinculin; Vinculin family
-
NM_001282599.2 → NP_001269528.1 catenin alpha-2 isoform 5
See identical proteins and their annotated locations for NP_001269528.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and has multiple coding region differences compared to variant 3. These differences include translation initiation at an alternate AUG start codon. The resulting isoform (5) has a shorter and distinct N-terminus and lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
BC052996, BX537769
- Consensus CDS
-
CCDS62945.1
- UniProtKB/Swiss-Prot
-
P26232
- Related
- ENSP00000341500.3, ENST00000343114.7
- Conserved Domains (1) summary
-
- pfam01044
Location:32 → 545
- Vinculin; Vinculin family
-
NM_001282600.2 → NP_001269529.1 catenin alpha-2 isoform 6
See identical proteins and their annotated locations for NP_001269529.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) has an alternate exon in the 5' UTR and has multiple coding region differences compared to variant 3. These differences include translation initiation at a downstream AUG start codon. The resulting isoform (6) is shorter at the N-terminus and lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
BC052996, BI599815, HQ589336
- Consensus CDS
-
CCDS74531.1
- UniProtKB/Swiss-Prot
-
P26232
- UniProtKB/TrEMBL
-
F6KRI5
- Related
- ENSP00000444675.2, ENST00000541047.5
- Conserved Domains (1) summary
-
- pfam01044
Location:1 → 498
- Vinculin; Vinculin family
-
NM_001320810.2 → NP_001307739.1 catenin alpha-2 isoform 7
Status: VALIDATED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 3. This difference includes translation initiation at a downstream AUG start codon. The resulting isoform (7) is shorter at the N-terminus compared to isoform 3.
- Source sequence(s)
-
AC008067, BI599815, BX648368, M94151
- UniProtKB/Swiss-Prot
-
P26232
- Related
- ENSP00000355398.5, ENST00000361291.8
- Conserved Domains (1) summary
-
- pfam01044
Location:1 → 546
- Vinculin; Vinculin family
-
NM_004389.4 → NP_004380.2 catenin alpha-2 isoform 1
See identical proteins and their annotated locations for NP_004380.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) lacks an in-frame exon in the 3' coding region compared to variant 3. The resulting isoform (1) lacks an internal segment near the C-terminus compared to isoform 3.
- Source sequence(s)
-
BC040458, BC052996, DA313393
- Consensus CDS
-
CCDS42703.2
- UniProtKB/Swiss-Prot
-
P26232
- UniProtKB/TrEMBL
-
Q49AD3
- Related
- ENSP00000419295.1, ENST00000496558.5
- Conserved Domains (1) summary
-
- pfam01044
Location:18 → 866
- Vinculin; Vinculin family