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CCDC17 coiled-coil domain containing 17 [ Homo sapiens (human) ]

Gene ID: 149483, updated on 12-Aug-2022

Summary

Official Symbol
CCDC17provided by HGNC
Official Full Name
coiled-coil domain containing 17provided by HGNC
Primary source
HGNC:HGNC:26574
See related
Ensembl:ENSG00000159588 AllianceGenome:HGNC:26574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in lung (RPKM 4.2), bone marrow (RPKM 0.8) and 18 other tissues See more
Orthologs
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Genomic context

See CCDC17 in Genome Data Viewer
Location:
1p34.1
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (45620044..45624054, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (45492399..45496409, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (46085716..46089726, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene aldo-keto reductase family 1 member A1 Neighboring gene nuclear autoantigenic sperm protein Neighboring gene GC-rich promoter binding protein 1 like 1 Neighboring gene ribosomal protein S15a pseudogene 10 Neighboring gene ribosomal protein L7a pseudogene 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ17921, FLJ33084

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
coiled-coil domain-containing protein 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114938.3NP_001108410.2  coiled-coil domain-containing protein 17 isoform 1

    See identical proteins and their annotated locations for NP_001108410.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK303939, AL355480, BU677500, DC359257
    Consensus CDS
    CCDS44131.2
    UniProtKB/Swiss-Prot
    Q5T629, Q96LX7
    Related
    ENSP00000432172.1, ENST00000528266.6
    Conserved Domains (1) summary
    TIGR01843
    Location:76217
    type_I_hlyD; type I secretion membrane fusion protein, HlyD family
  2. NM_001190182.2NP_001177111.1  coiled-coil domain-containing protein 17 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
    Source sequence(s)
    AK298104, AL355480, BU677500
    Consensus CDS
    CCDS53314.1
    UniProtKB/Swiss-Prot
    Q96LX7
    Related
    ENSP00000389415.2, ENST00000421127.6
    Conserved Domains (1) summary
    COG1196
    Location:127308
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    45620044..45624054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017000455.2XP_016855944.1  coiled-coil domain-containing protein 17 isoform X9

  2. XM_017000454.2XP_016855943.1  coiled-coil domain-containing protein 17 isoform X7

  3. XM_017000451.2XP_016855940.1  coiled-coil domain-containing protein 17 isoform X4

  4. XM_017000450.2XP_016855939.1  coiled-coil domain-containing protein 17 isoform X2

  5. XM_017000452.2XP_016855941.1  coiled-coil domain-containing protein 17 isoform X5

  6. XM_017000453.2XP_016855942.1  coiled-coil domain-containing protein 17 isoform X6

  7. XM_011540814.2XP_011539116.1  coiled-coil domain-containing protein 17 isoform X3

    Related
    ENST00000491755.5
    Conserved Domains (1) summary
    TIGR02169
    Location:219346
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
  8. XM_011540812.2XP_011539114.1  coiled-coil domain-containing protein 17 isoform X1

    Conserved Domains (1) summary
    TIGR02169
    Location:219346
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
  9. XM_017000456.1XP_016855945.1  coiled-coil domain-containing protein 17 isoform X9

  10. XM_047447377.1XP_047303333.1  coiled-coil domain-containing protein 17 isoform X8

    UniProtKB/TrEMBL
    F2Z395
    Related
    ENSP00000437072.1, ENST00000479529.2
  11. XM_011540820.2XP_011539122.1  coiled-coil domain-containing protein 17 isoform X10

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    45492399..45496409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_152500.2: Suppressed sequence

    Description
    NM_152500.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.