Format

Send to:

Choose Destination

KNCN kinocilin [ Homo sapiens (human) ]

Gene ID: 148930, updated on 23-Nov-2021

Summary

Official Symbol
KNCNprovided by HGNC
Official Full Name
kinocilinprovided by HGNC
Primary source
HGNC:HGNC:26488
See related
Ensembl:ENSG00000162456 MIM:611455
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L5; Kino
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See KNCN in Genome Data Viewer
Location:
1p33
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (46545641..46551647, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (47011313..47017319, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr1.5857 Neighboring gene transmembrane protein 275 Neighboring gene MKNK1 antisense RNA 1 Neighboring gene MAPK interacting serine/threonine kinase 1 Neighboring gene MOB kinase activator 3C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ32011, MGC120370, MGC120371, MGC120372

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cuticular plate IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in kinocilium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097611.1NP_001091080.1  kinocilin isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL136373, DA208279, DB324949
    Consensus CDS
    CCDS44133.1
    UniProtKB/Swiss-Prot
    A6PVL3
    Related
    ENSP00000379607.3, ENST00000396314.3
    Conserved Domains (1) summary
    pfam15033
    Location:193
    Kinocilin; Kinocilin protein
  2. NM_001322255.2NP_001309184.1  kinocilin isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL136373
    Consensus CDS
    CCDS81316.1
    UniProtKB/Swiss-Prot
    A6PVL3
    Related
    ENSP00000419705.3, ENST00000481882.7
    Conserved Domains (1) summary
    pfam15033
    Location:1116
    Kinocilin; Kinocilin protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    46545641..46551647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_182516.1: Suppressed sequence

    Description
    NM_182516.1: This RefSeq was permanently suppressed because it contains the wrong CDS.
Support Center