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MFSD4A major facilitator superfamily domain containing 4A [ Homo sapiens (human) ]

Gene ID: 148808, updated on 11-Jun-2021

Summary

Official Symbol
MFSD4Aprovided by HGNC
Official Full Name
major facilitator superfamily domain containing 4Aprovided by HGNC
Primary source
HGNC:HGNC:25433
See related
Ensembl:ENSG00000174514
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MFSD4; SLC60A1; UNQ3064
Expression
Biased expression in kidney (RPKM 40.9), stomach (RPKM 37.2) and 6 other tissues See more
Orthologs
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Genomic context

See MFSD4A in Genome Data Viewer
Location:
1q32.1
Exon count:
10
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (205569014..205602918)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (205538142..205572046)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 18 Neighboring gene MFSD4A antisense RNA 1 Neighboring gene RNA, U2 small nuclear 19, pseudogene Neighboring gene Sharpr-MPRA regulatory region 9898 Neighboring gene RNA, U6 small nuclear 418, pseudogene Neighboring gene GABA type A receptor-associated protein pseudogene Neighboring gene ETS transcription factor ELK4 Neighboring gene solute carrier family 45 member 3 Neighboring gene uncharacterized LOC105371701

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25004, FLJ34577, FLJ45392, DKFZp564C1416, DKFZp761N1114

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in glucose transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
major facilitator superfamily domain-containing protein 4A
Names
major facilitator superfamily domain containing 4
major facilitator superfamily domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181644.5NP_857595.3  major facilitator superfamily domain-containing protein 4A

    See identical proteins and their annotated locations for NP_857595.3

    Status: VALIDATED

    Source sequence(s)
    AK090831, AK091896, BC016377, BC036549, DC317463
    Consensus CDS
    CCDS1455.1
    UniProtKB/Swiss-Prot
    Q8N468
    UniProtKB/TrEMBL
    Q96KX6
    Related
    ENSP00000356115.4, ENST00000367147.9
    Conserved Domains (1) summary
    cd06174
    Location:18160
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    205569014..205602918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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