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Gstm3 glutathione S-transferase, mu 3 [ Mus musculus (house mouse) ]

Gene ID: 14864, updated on 25-Sep-2020

Summary

Official Symbol
Gstm3provided by MGI
Official Full Name
glutathione S-transferase, mu 3provided by MGI
Primary source
MGI:MGI:106026
See related
Ensembl:ENSMUSG00000004038
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fsc; Fsc2; mGSTM; mGSTM5
Expression
Biased expression in duodenum adult (RPKM 983.2), small intestine adult (RPKM 137.5) and 2 other tissues See more

Genomic context

See Gstm3 in Genome Data Viewer
Location:
3; 3 F2.3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (107871012..107876490, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (107963696..107969174, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (107766614..107772076, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase, mu 7 Neighboring gene glutathione S-transferase, mu 6 Neighboring gene predicted pseudogene 12497 Neighboring gene glutathione S-transferase, mu 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutathione transferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to drug IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to organic cyclic compound IDA
Inferred from Direct Assay
more info
PubMed 
glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glutathione S-transferase Mu 3
Names
GST class-mu 3
glutathione S-transferase GT9.3
NP_034489.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010359.2NP_034489.1  glutathione S-transferase Mu 3

    See identical proteins and their annotated locations for NP_034489.1

    Status: VALIDATED

    Source sequence(s)
    AC079042
    Consensus CDS
    CCDS17744.1
    UniProtKB/Swiss-Prot
    P19639
    Related
    ENSMUSP00000004136.8, ENSMUST00000004136.9
    Conserved Domains (3) summary
    cd03209
    Location:92212
    GST_C_Mu; C-terminal, alpha helical domain of Class Mu Glutathione S-transferases
    COG0625
    Location:3189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    cd03075
    Location:384
    GST_N_Mu; GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    107871012..107876490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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