U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pyrH UMP kinase [ Archaeoglobus fulgidus DSM 4304 ]

Gene ID: 1485269, updated on 23-Nov-2025
Gene symbol
pyrH
Gene description
UMP kinase
Locus tag
AF_RS10275
Gene type
protein coding
Organism
Archaeoglobus fulgidus DSM 4304 (strain: DSM 4304, type-material: type strain of Archaeoglobus fulgidus)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus
Old locus tag
AF2042; AF_2042
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000917.1 (1843239..1843898)

NC_000917.1Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene DUF4386 domain-containing protein Neighboring gene dihydroneopterin aldolase family protein Neighboring gene CDP-diacylglycerol--serine O-phosphatidyltransferase Neighboring gene archaetidylserine decarboxylase Neighboring gene archaeosortase A

Genomic Sequence:
NC_000917.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation. Jensen KS, et al. Biochemistry, 2007 Mar 13. PMID 17297917
  2. The crystal structure of Pyrococcus furiosus UMP kinase provides insight into catalysis and regulation in microbial pyrimidine nucleotide biosynthesis. Marco-Marín C, et al. J Mol Biol, 2005 Sep 16. PMID 16095620
  3. The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus. Klenk HP, et al. Nature, 1997 Nov 27. PMID 9389475

GeneRIFs: Gene References Into Functions

Preferred Names
UMP kinase
WP_010879534.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000917.1 Reference assembly

    Range
    1843239..1843898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010879534.1 UMP kinase

    See identical proteins and their annotated locations for WP_010879534.1

    UniProtKB/Swiss-Prot
    O28237
    UniProtKB/TrEMBL
    A0A075WGZ3, A0A101DZS3
    Conserved Domains (1) summary
    cd04253
    Location:2 → 218
    AAK_UMPK-PyrH-Pf; AAK_UMPK-PyrH-Pf: UMP kinase (UMPK)-Pf, the mostly archaeal uridine monophosphate kinase (uridylate kinase) enzymes that catalyze UMP phosphorylation and play a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O28237.1