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CTAG1B cancer/testis antigen 1B [ Homo sapiens (human) ]

Gene ID: 1485, updated on 23-Dec-2018

Summary

Official Symbol
CTAG1Bprovided by HGNC
Official Full Name
cancer/testis antigen 1Bprovided by HGNC
Primary source
HGNC:HGNC:2491
See related
Ensembl:ENSG00000184033 MIM:300156
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1
Summary
The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]
Expression
Restricted expression toward testis (RPKM 4.5) See more

Genomic context

See CTAG1B in Genome Data Viewer
Location:
Xq28
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) X NC_000023.11 (154617609..154619271, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (153845865..153847522, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene activating transcription factor 4 pseudogene 2 Neighboring gene cancer/testis antigen 1A Neighboring gene activating transcription factor 4 pseudogene 1 Neighboring gene family with sequence similarity 223 member B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
cancer/testis antigen 1
Names
New York esophageal squamous cell carcinoma 1
autoimmunogenic cancer/testis antigen NY-ESO-1
cancer antigen 3
cancer/testis antigen 6.1
l antigen family member 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001327.2NP_001318.1  cancer/testis antigen 1

    See identical proteins and their annotated locations for NP_001318.1

    Status: REVIEWED

    Source sequence(s)
    U87459
    Consensus CDS
    CCDS14758.1
    UniProtKB/Swiss-Prot
    P78358
    Related
    ENSP00000332602.2, ENST00000328435.2
    Conserved Domains (1) summary
    pfam09341
    Location:92162
    Pcc1; Transcription factor Pcc1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p12 Primary Assembly

    Range
    154617609..154619271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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