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ZNF569 zinc finger protein 569 [ Homo sapiens (human) ]

Gene ID: 148266, updated on 23-Nov-2021

Summary

Official Symbol
ZNF569provided by HGNC
Official Full Name
zinc finger protein 569provided by HGNC
Primary source
HGNC:HGNC:24737
See related
Ensembl:ENSG00000196437 MIM:613904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF; ZAP1; Zfp74
Expression
Broad expression in testis (RPKM 4.0), thyroid (RPKM 2.7) and 24 other tissues See more
Orthologs
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Genomic context

See ZNF569 in Genome Data Viewer
Location:
19q13.12
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (37411146..37469263, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (37902059..37958346, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 875 Neighboring gene zinc finger protein 527 Neighboring gene zinc finger protein 570 Neighboring gene ZNF793 antisense RNA 1 (head to head) Neighboring gene zinc finger protein 793 Neighboring gene ZNF571 antisense RNA 1 Neighboring gene zinc finger protein 540 Neighboring gene MT-ND4 pseudogene 41 Neighboring gene zinc finger protein 571

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32053

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 569
Names
DNA-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330482.2NP_001317411.1  zinc finger protein 569 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC008806
    Consensus CDS
    CCDS82341.1
    UniProtKB/Swiss-Prot
    Q5MCW4
    Conserved Domains (2) summary
    COG5048
    Location:109521
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:85105
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_152484.3NP_689697.2  zinc finger protein 569 isoform 1

    See identical proteins and their annotated locations for NP_689697.2

    Status: VALIDATED

    Source sequence(s)
    AC008806, AK122846, AL833408, BC038737, CB151734
    Consensus CDS
    CCDS12503.1
    UniProtKB/Swiss-Prot
    Q5MCW4
    UniProtKB/TrEMBL
    A0A024R0G4
    Related
    ENSP00000325018.5, ENST00000316950.11
    Conserved Domains (3) summary
    smart00349
    Location:862
    KRAB; krueppel associated box
    COG5048
    Location:268680
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    37411146..37469263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006723048.4XP_006723111.1  zinc finger protein 569 isoform X1

    See identical proteins and their annotated locations for XP_006723111.1

    Conserved Domains (3) summary
    smart00349
    Location:3286
    KRAB; krueppel associated box
    COG5048
    Location:292704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:268288
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_017026382.2XP_016881871.1  zinc finger protein 569 isoform X3

    UniProtKB/Swiss-Prot
    Q5MCW4
    Conserved Domains (2) summary
    COG5048
    Location:109521
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:85105
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_017026377.2XP_016881866.1  zinc finger protein 569 isoform X2

    UniProtKB/Swiss-Prot
    Q5MCW4
    UniProtKB/TrEMBL
    A0A024R0G4
    Conserved Domains (3) summary
    smart00349
    Location:862
    KRAB; krueppel associated box
    COG5048
    Location:268680
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_017026379.1XP_016881868.1  zinc finger protein 569 isoform X3

    UniProtKB/Swiss-Prot
    Q5MCW4
    Conserved Domains (2) summary
    COG5048
    Location:109521
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:85105
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006723046.2XP_006723109.1  zinc finger protein 569 isoform X1

    See identical proteins and their annotated locations for XP_006723109.1

    Related
    ENSP00000466221.2, ENST00000448051.7
    Conserved Domains (3) summary
    smart00349
    Location:3286
    KRAB; krueppel associated box
    COG5048
    Location:292704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:268288
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011526538.3XP_011524840.1  zinc finger protein 569 isoform X1

    See identical proteins and their annotated locations for XP_011524840.1

    Conserved Domains (3) summary
    smart00349
    Location:3286
    KRAB; krueppel associated box
    COG5048
    Location:292704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:268288
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_006723047.4XP_006723110.1  zinc finger protein 569 isoform X1

    See identical proteins and their annotated locations for XP_006723110.1

    Conserved Domains (3) summary
    smart00349
    Location:3286
    KRAB; krueppel associated box
    COG5048
    Location:292704
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:268288
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_017026376.1XP_016881865.1  zinc finger protein 569 isoform X2

    UniProtKB/Swiss-Prot
    Q5MCW4
    UniProtKB/TrEMBL
    A0A024R0G4
    Conserved Domains (3) summary
    smart00349
    Location:862
    KRAB; krueppel associated box
    COG5048
    Location:268680
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_017026380.1XP_016881869.1  zinc finger protein 569 isoform X3

    UniProtKB/Swiss-Prot
    Q5MCW4
    Related
    ENSP00000375993.2, ENST00000392150.2
    Conserved Domains (2) summary
    COG5048
    Location:109521
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:85105
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. XM_011526539.3XP_011524841.1  zinc finger protein 569 isoform X2

    See identical proteins and their annotated locations for XP_011524841.1

    UniProtKB/Swiss-Prot
    Q5MCW4
    UniProtKB/TrEMBL
    A0A024R0G4
    Related
    ENSP00000375992.2, ENST00000392149.6
    Conserved Domains (3) summary
    smart00349
    Location:862
    KRAB; krueppel associated box
    COG5048
    Location:268680
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]
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