NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_144691.4 → NP_653292.2 calpain-12
See identical proteins and their annotated locations for NP_653292.2
Status: VALIDATED
- Source sequence(s)
-
AC022144, AK127398, BE872274, DA384049
- Consensus CDS
-
CCDS12519.1
- UniProtKB/Swiss-Prot
-
Q6ZSI9
- Related
- ENSP00000331636.3, ENST00000328867.9
- Conserved Domains (3) summary
-
- cd00214
Location:352 → 530
- Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
- pfam00648
Location:46 → 339
- Peptidase_C2; Calpain family cysteine protease
- cl08302
Location:626 → 681
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...