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Cdca3 cell division cycle associated 3 [ Mus musculus (house mouse) ]

Gene ID: 14793, updated on 2-Nov-2024

Summary

Official Symbol
Cdca3provided by MGI
Official Full Name
cell division cycle associated 3provided by MGI
Primary source
MGI:MGI:1315198
See related
Ensembl:ENSMUSG00000023505 AllianceGenome:MGI:1315198
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C8; Grcc8; Tome-1; 2410005A12Rik
Summary
Predicted to be involved in cell division and protein ubiquitination. Predicted to be located in adherens junction. Is expressed in several structures, including brain; liver lobe; olfactory epithelium; orbito-sphenoid; and renal cortex. Orthologous to human CDCA3 (cell division cycle associated 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in liver E14.5 (RPKM 51.6), liver E14 (RPKM 50.2) and 17 other tissues See more
Orthologs
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Genomic context

See Cdca3 in Genome Data Viewer
Location:
6 F2; 6 59.17 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (124806533..124810664)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (124829530..124833701)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene splA/ryanodine receptor domain and SOCS box containing 2 Neighboring gene STARR-positive B cell enhancer mm9_chr6:124764120-124764420 Neighboring gene triosephosphate isomerase 1 Neighboring gene ubiquitin specific peptidase 5 (isopeptidase T) Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:124778211-124778394 Neighboring gene guanine nucleotide binding protein (G protein), beta 3 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene STARR-positive B cell enhancer ABC_E6487

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 
located_in adherens junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cell division cycle-associated protein 3
Names
gene rich cluster, C8
gene-rich cluster protein C8
trigger of mitotic entry 1
trigger of mitotic entry protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013538.5NP_038566.1  cell division cycle-associated protein 3

    See identical proteins and their annotated locations for NP_038566.1

    Status: VALIDATED

    Source sequence(s)
    AK010409, AK145537, BB860939
    Consensus CDS
    CCDS39629.1
    UniProtKB/Swiss-Prot
    O88837, Q8R2V1, Q99M54
    UniProtKB/TrEMBL
    D3Z3H6
    Related
    ENSMUSP00000024270.8, ENSMUST00000024270.14
    Conserved Domains (1) summary
    PHA03269
    Location:41216
    PHA03269; envelope glycoprotein C; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    124806533..124810664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505564.5XP_006505627.1  cell division cycle-associated protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006505627.1

    UniProtKB/Swiss-Prot
    O88837, Q8R2V1, Q99M54
    UniProtKB/TrEMBL
    D3Z3H6
    Conserved Domains (1) summary
    PHA03269
    Location:41216
    PHA03269; envelope glycoprotein C; Provisional