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KASH5 KASH domain containing 5 [ Homo sapiens (human) ]

Gene ID: 147872, updated on 2-Mar-2021

Summary

Official Symbol
KASH5provided by HGNC
Official Full Name
KASH domain containing 5provided by HGNC
Primary source
HGNC:HGNC:26520
See related
Ensembl:ENSG00000161609 MIM:618125
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCDC155
Expression
Restricted expression toward testis (RPKM 13.2) See more
Orthologs
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Genomic context

See KASH5 in Genome Data Viewer
Location:
19q13.33
Exon count:
24
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (49388218..49418002)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (49891506..49921247)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CD37 molecule Neighboring gene TEA domain transcription factor 2 Neighboring gene uncharacterized LOC101928295 Neighboring gene dickkopf like acrosomal protein 1 Neighboring gene parathyroid hormone 2 Neighboring gene golgi associated olfactory signaling regulator

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32658, DKFZp434A2223

Gene Ontology Provided by GOA

Function Evidence Code Pubs
dynein complex binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromosome localization to nuclear envelope involved in homologous chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 
homologous chromosome pairing at meiosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule cytoskeleton organization involved in homologous chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oogenesis IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
telomere localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
chromosome, telomeric region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromosome, telomeric region ISS
Inferred from Sequence or Structural Similarity
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
lateral element IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
meiotic nuclear membrane microtubule tethering complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
meiotic spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein KASH5
Names
KASH domain-containing protein 5
coiled-coil domain containing 155
NP_653289.3
XP_005258606.1
XP_011524790.1
XP_011524791.1
XP_011524792.1
XP_011524796.1
XP_011524797.1
XP_011524798.1
XP_011524799.1
XP_016881822.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144688.5NP_653289.3  protein KASH5

    See identical proteins and their annotated locations for NP_653289.3

    Status: VALIDATED

    Source sequence(s)
    AK057220, DB024870, DB517121
    Consensus CDS
    CCDS46140.1
    UniProtKB/Swiss-Prot
    Q8N6L0
    Related
    ENSP00000404220.2, ENST00000447857.8
    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    49388218..49418002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526488.2XP_011524790.1  protein KASH5 isoform X1

    See identical proteins and their annotated locations for XP_011524790.1

    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein
  2. XM_005258549.3XP_005258606.1  protein KASH5 isoform X4

    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein
  3. XM_011526490.2XP_011524792.1  protein KASH5 isoform X2

    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein
  4. XM_011526496.2XP_011524798.1  protein KASH5 isoform X6

    See identical proteins and their annotated locations for XP_011524798.1

    Related
    ENSP00000470819.1, ENST00000600570.1
    Conserved Domains (4) summary
    COG3352
    Location:184327
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:1178
    EF-hand_9; EF-hand domain
    pfam14662
    Location:146321
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:170246
    FAM76; FAM76 protein
  5. XM_011526495.2XP_011524797.1  protein KASH5 isoform X6

    See identical proteins and their annotated locations for XP_011524797.1

    Conserved Domains (4) summary
    COG3352
    Location:184327
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:1178
    EF-hand_9; EF-hand domain
    pfam14662
    Location:146321
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:170246
    FAM76; FAM76 protein
  6. XM_011526494.2XP_011524796.1  protein KASH5 isoform X5

    Conserved Domains (4) summary
    COG3352
    Location:197340
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:2491
    EF-hand_9; EF-hand domain
    pfam14662
    Location:159334
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:183259
    FAM76; FAM76 protein
  7. XM_011526489.3XP_011524791.1  protein KASH5 isoform X1

    See identical proteins and their annotated locations for XP_011524791.1

    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein
  8. XM_011526497.2XP_011524799.1  protein KASH5 isoform X1

    See identical proteins and their annotated locations for XP_011524799.1

    Conserved Domains (4) summary
    COG3352
    Location:211354
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:38105
    EF-hand_9; EF-hand domain
    pfam14662
    Location:173348
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:197273
    FAM76; FAM76 protein
  9. XM_017026333.1XP_016881822.1  protein KASH5 isoform X3

    Conserved Domains (4) summary
    COG3352
    Location:205348
    FlaC; Archaellum component FlaC [Cell motility]
    pfam14658
    Location:3299
    EF-hand_9; EF-hand domain
    pfam14662
    Location:167342
    KASH_CCD; Coiled-coil region of CCDC155 or KASH
    pfam16046
    Location:191267
    FAM76; FAM76 protein
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