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TMEM190 transmembrane protein 190 [ Homo sapiens (human) ]

Gene ID: 147744, updated on 22-Sep-2022

Summary

Official Symbol
TMEM190provided by HGNC
Official Full Name
transmembrane protein 190provided by HGNC
Primary source
HGNC:HGNC:29632
See related
Ensembl:ENSG00000160472 AllianceGenome:HGNC:29632
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MDAC1
Summary
Predicted to enable protein self-association. Predicted to be involved in hematopoietic progenitor cell differentiation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 4.0), lung (RPKM 3.5) and 1 other tissue See more
Orthologs
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Genomic context

See TMEM190 in Genome Data Viewer
Location:
19q13.42
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (55376826..55378246)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (58472347..58473732)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (55888194..55889614)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene interleukin 11 Neighboring gene CRISPRi-validated cis-regulatory element chr19.6204 Neighboring gene transmembrane protein 238 Neighboring gene ribosomal protein L28 Neighboring gene microRNA 6805

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC149301, MGC149302

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein self-association IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in hematopoietic progenitor cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in inner acrosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus HDA PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139172.3NP_631911.1  transmembrane protein 190 precursor

    See identical proteins and their annotated locations for NP_631911.1

    Status: VALIDATED

    Source sequence(s)
    AF442729, HY050559, HY223996
    Consensus CDS
    CCDS33113.1
    UniProtKB/Swiss-Prot
    A6NJL5, Q8WZ59
    Related
    ENSP00000291934.3, ENST00000291934.4
    Conserved Domains (1) summary
    pfam15431
    Location:21145
    TMEM190; Transmembrane protein 190

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    55376826..55378246
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026331.2XP_016881820.1  transmembrane protein 190 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    58472347..58473732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)