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ZNF560 zinc finger protein 560 [ Homo sapiens (human) ]

Gene ID: 147741, updated on 23-Nov-2021

Summary

Official Symbol
ZNF560provided by HGNC
Official Full Name
zinc finger protein 560provided by HGNC
Primary source
HGNC:HGNC:26484
See related
Ensembl:ENSG00000198028
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 2.9) See more
Orthologs
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Genomic context

See ZNF560 in Genome Data Viewer
Location:
19p13.2
Exon count:
13
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (9445710..9506692, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9577031..9609292, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268250 Neighboring gene zinc finger protein 266 Neighboring gene endogenous retrovirus group K member 8 Gag polyprotein-like Neighboring gene uncharacterized LOC105372268 Neighboring gene actin beta pseudogene Neighboring gene zinc finger protein 426 Neighboring gene ZNF426 divergent transcript

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Clone Names

  • FLJ31986, MGC119490, MGC119493

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054924.1 RefSeqGene

    Range
    13077..45338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001351678.2NP_001338607.1  zinc finger protein 560 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction in the 5' end and uses a downstream start codon compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC008567, AK056548, BC101039
    Conserved Domains (4) summary
    smart00349
    Location:455
    KRAB; krueppel associated box
    COG5048
    Location:238648
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:608628
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:651673
    zf-H2C2_2; Zinc-finger double domain
  2. NM_152476.3NP_689689.2  zinc finger protein 560 isoform 1

    See identical proteins and their annotated locations for NP_689689.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC008567, BC101040, DA744260, T41372
    Consensus CDS
    CCDS12214.1
    UniProtKB/Swiss-Prot
    Q96MR9
    Related
    ENSP00000301480.3, ENST00000301480.5
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    9445710..9506692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527697.2XP_011525999.1  zinc finger protein 560 isoform X1

    See identical proteins and their annotated locations for XP_011525999.1

    UniProtKB/Swiss-Prot
    Q96MR9
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain
  2. XM_024451380.1XP_024307148.1  zinc finger protein 560 isoform X2

    Conserved Domains (5) summary
    smart00349
    Location:69120
    KRAB; krueppel associated box
    COG5048
    Location:303713
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:673693
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:716738
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:128
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. XM_017026328.1XP_016881817.1  zinc finger protein 560 isoform X1

    UniProtKB/Swiss-Prot
    Q96MR9
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain
  4. XM_017026329.1XP_016881818.1  zinc finger protein 560 isoform X1

    UniProtKB/Swiss-Prot
    Q96MR9
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain
  5. XM_017026327.1XP_016881816.1  zinc finger protein 560 isoform X1

    UniProtKB/Swiss-Prot
    Q96MR9
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain
  6. XM_017026330.1XP_016881819.1  zinc finger protein 560 isoform X3

    Conserved Domains (4) summary
    smart00349
    Location:455
    KRAB; krueppel associated box
    COG5048
    Location:238648
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:608628
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:651673
    zf-H2C2_2; Zinc-finger double domain
  7. XM_011527696.2XP_011525998.1  zinc finger protein 560 isoform X1

    See identical proteins and their annotated locations for XP_011525998.1

    UniProtKB/Swiss-Prot
    Q96MR9
    Conserved Domains (6) summary
    smart00349
    Location:1369
    KRAB; krueppel associated box
    COG5048
    Location:344754
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:714734
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:600622
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1350
    KRAB; KRAB box
    pfam13465
    Location:726751
    zf-H2C2_2; Zinc-finger double domain
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