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IGSF23 immunoglobulin superfamily member 23 [ Homo sapiens (human) ]

Gene ID: 147710, updated on 22-Sep-2022

Summary

Official Symbol
IGSF23provided by HGNC
Official Full Name
immunoglobulin superfamily member 23provided by HGNC
Primary source
HGNC:HGNC:40040
See related
Ensembl:ENSG00000216588 AllianceGenome:HGNC:40040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a protein that has one immunoglobulin (Ig) domain and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by RefSeq, Nov 2011]
Expression
Biased expression in small intestine (RPKM 1.4), duodenum (RPKM 1.3) and 3 other tissues See more
Orthologs
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Genomic context

See IGSF23 in Genome Data Viewer
Location:
19q13.31
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (44613563..44636781)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (47438308..47461513)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45116873..45140081)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CEA cell adhesion molecule 20 Neighboring gene CEA cell adhesion molecule 22, pseudogene Neighboring gene Sharpr-MPRA regulatory region 2639 Neighboring gene microRNA 4531 Neighboring gene PVR cell adhesion molecule Neighboring gene CEA cell adhesion molecule 19

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
immunoglobulin superfamily member 23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_030649.2 RefSeqGene

    Range
    5002..28220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001205280.2NP_001192209.1  immunoglobulin superfamily member 23

    See identical proteins and their annotated locations for NP_001192209.1

    Status: REVIEWED

    Source sequence(s)
    AC243964, BG197674, BX112065
    Consensus CDS
    CCDS54277.1
    UniProtKB/Swiss-Prot
    A1L1A6
    Related
    ENSP00000385592.1, ENST00000402988.6
    Conserved Domains (1) summary
    cl11960
    Location:66117
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    44613563..44636781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    47438308..47461513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)