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C19orf18 chromosome 19 open reading frame 18 [ Homo sapiens (human) ]

Gene ID: 147685, updated on 5-Jan-2022

Summary

Official Symbol
C19orf18provided by HGNC
Official Full Name
chromosome 19 open reading frame 18provided by HGNC
Primary source
HGNC:HGNC:28642
See related
Ensembl:ENSG00000177025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in extracellular exosome. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in testis (RPKM 4.2), heart (RPKM 0.8) and 15 other tissues See more
Orthologs
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Genomic context

See C19orf18 in Genome Data Viewer
Location:
19q13.43
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (57958437..57974534, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (58469805..58485902, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 256 Neighboring gene ribosomal protein L19 pseudogene 19 Neighboring gene zinc finger protein 606 Neighboring gene uncharacterized LOC100128398 Neighboring gene vomeronasal 2 receptor 19, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Potential readthrough

Included gene: ZNF606

Homology

Clone Names

  • MGC41906

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein C19orf18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152474.5NP_689687.1  uncharacterized protein C19orf18 precursor

    See identical proteins and their annotated locations for NP_689687.1

    Status: VALIDATED

    Source sequence(s)
    BC033933
    Consensus CDS
    CCDS12967.1
    UniProtKB/Swiss-Prot
    Q8NEA5
    Related
    ENSP00000321519.2, ENST00000314391.3

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    57958437..57974534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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