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Gpr19 G protein-coupled receptor 19 [ Mus musculus (house mouse) ]

Gene ID: 14760, updated on 26-Apr-2018
Official Symbol
Gpr19provided by MGI
Official Full Name
G protein-coupled receptor 19provided by MGI
Primary source
MGI:MGI:892973
See related
Ensembl:ENSMUSG00000032641 Vega:OTTMUSG00000024355
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in testis adult (RPKM 6.5), whole brain E14.5 (RPKM 5.0) and 28 other tissues See more
Orthologs
See Gpr19 in Genome Data Viewer
Location:
6; 6 G1
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (134869092..134899482, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (134819111..134847943, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700055D16 gene Neighboring gene cAMP responsive element binding protein-like 2 Neighboring gene RIKEN cDNA 2810454H06 gene Neighboring gene predicted gene, 40407 Neighboring gene cyclin-dependent kinase inhibitor 1B Neighboring gene lncRNA downstream of Cdkn1b

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
probable G-protein coupled receptor 19

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167694.2NP_001161166.1  probable G-protein coupled receptor 19 isoform a

    See identical proteins and their annotated locations for NP_001161166.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longer isoform (a). Variants 3, 6 and 7 all encode isoform a.
    Source sequence(s)
    AC122193, AK140770, BY712856, DV660907
    Consensus CDS
    CCDS51937.1
    UniProtKB/Swiss-Prot
    Q61121
    Related
    ENSMUSP00000047630.7, OTTMUSP00000029039, ENSMUST00000046255.13, OTTMUST00000059660
    Conserved Domains (2) summary
    pfam00001
    Location:82330
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:72258
    7tm_4; Olfactory receptor
  2. NM_001167695.2NP_001161167.1  probable G-protein coupled receptor 19 isoform b

    See identical proteins and their annotated locations for NP_001161167.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 3. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Variants 1, 2, 4, 5, and 8-12 all encode isoform b.
    Source sequence(s)
    AC122193, AK140770
    Consensus CDS
    CCDS20641.1
    UniProtKB/Swiss-Prot
    Q61121
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_001167696.2NP_001161168.1  probable G-protein coupled receptor 19 isoform b

    See identical proteins and their annotated locations for NP_001161168.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 3. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Variants 1, 2, 4, 5, and 8-12 all encode isoform b.
    Source sequence(s)
    AC122193, AK132917, DV651999
    Consensus CDS
    CCDS20641.1
    UniProtKB/Swiss-Prot
    Q61121
    Related
    ENSMUSP00000127876.1, ENSMUST00000165392.7
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  4. NM_001167697.2NP_001161169.1  probable G-protein coupled receptor 19 isoform a

    See identical proteins and their annotated locations for NP_001161169.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 3. Variants 3, 6 and 7 all encode isoform a.
    Source sequence(s)
    AC122193, AK132917, BB853775, BQ558507
    Consensus CDS
    CCDS51937.1
    UniProtKB/Swiss-Prot
    Q61121
    Conserved Domains (2) summary
    pfam00001
    Location:82330
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:72258
    7tm_4; Olfactory receptor
  5. NM_001167699.2NP_001161171.1  probable G-protein coupled receptor 19 isoform a

    See identical proteins and their annotated locations for NP_001161171.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 3. Variants 3, 6 and 7 all encode isoform a.
    Source sequence(s)
    AC122193, AK132917, BB853775, BQ558507, BY275399, BY291247
    Consensus CDS
    CCDS51937.1
    UniProtKB/Swiss-Prot
    Q61121
    Conserved Domains (2) summary
    pfam00001
    Location:82330
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:72258
    7tm_4; Olfactory receptor
  6. NM_001167700.2NP_001161172.1  probable G-protein coupled receptor 19 isoform b

    See identical proteins and their annotated locations for NP_001161172.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 3. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Variants 1, 2, 4, 5, and 8-12 all encode isoform b.
    Source sequence(s)
    AC122193, AK132917, BY712856
    Consensus CDS
    CCDS20641.1
    UniProtKB/Swiss-Prot
    Q61121
    Related
    ENSMUSP00000107563.1, OTTMUSP00000029038, ENSMUST00000111932.7, OTTMUST00000059659
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  7. NM_001362048.1NP_001348977.1  probable G-protein coupled receptor 19 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variants 2, 4, 5, and 8-12, encodes isoform b.
    Source sequence(s)
    AC122193
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  8. NM_001362049.1NP_001348978.1  probable G-protein coupled receptor 19 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 1, 2, 4, 5, 8, and 10-12, encodes isoform b.
    Source sequence(s)
    AC122193
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  9. NM_001362050.1NP_001348979.1  probable G-protein coupled receptor 19 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 1, 2, 4, 5, 8, 9, 11, and 12, encodes the same isoform (b).
    Source sequence(s)
    AC122193
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  10. NM_001362051.1NP_001348980.1  probable G-protein coupled receptor 19 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 1, 2, 4, 5, 8-10, and 12, encodes isoform b.
    Source sequence(s)
    AC122193
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  11. NM_001362052.1NP_001348981.1  probable G-protein coupled receptor 19 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 1, 2, 4, 5, and 8-11, encodes isoform b.
    Source sequence(s)
    AC122193
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  12. NM_008157.3NP_032183.2  probable G-protein coupled receptor 19 isoform b

    See identical proteins and their annotated locations for NP_032183.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 3. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Variants 1, 2, 4, 5, and 8-12 all encode isoform b.
    Source sequence(s)
    AC122193, AK132917, BB853775, BY275399
    Consensus CDS
    CCDS20641.1
    UniProtKB/Swiss-Prot
    Q61121
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. NR_155270.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122193, BY712856

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    134869092..134899482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505547.3XP_006505610.1  probable G-protein coupled receptor 19 isoform X1

    See identical proteins and their annotated locations for XP_006505610.1

    UniProtKB/TrEMBL
    A0A1N9MDH9
    Conserved Domains (2) summary
    pfam00001
    Location:168416
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:158344
    7tm_4; Olfactory receptor
  2. XM_006505544.3XP_006505607.1  probable G-protein coupled receptor 19 isoform X1

    See identical proteins and their annotated locations for XP_006505607.1

    UniProtKB/TrEMBL
    A0A1N9MDH9
    Conserved Domains (2) summary
    pfam00001
    Location:168416
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:158344
    7tm_4; Olfactory receptor
  3. XM_006505543.3XP_006505606.1  probable G-protein coupled receptor 19 isoform X1

    See identical proteins and their annotated locations for XP_006505606.1

    UniProtKB/TrEMBL
    A0A1N9MDH9
    Conserved Domains (2) summary
    pfam00001
    Location:168416
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:158344
    7tm_4; Olfactory receptor
  4. XM_006505545.2XP_006505608.1  probable G-protein coupled receptor 19 isoform X1

    See identical proteins and their annotated locations for XP_006505608.1

    UniProtKB/TrEMBL
    A0A1N9MDH9
    Conserved Domains (2) summary
    pfam00001
    Location:168416
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:158344
    7tm_4; Olfactory receptor
  5. XM_006505554.1XP_006505617.1  probable G-protein coupled receptor 19 isoform X3

    UniProtKB/Swiss-Prot
    Q61121
    Related
    ENSMUSP00000112214.2, ENSMUST00000116515.8
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  6. XM_017321391.1XP_017176880.1  probable G-protein coupled receptor 19 isoform X2

  7. XM_017321392.1XP_017176881.1  probable G-protein coupled receptor 19 isoform X2

  8. XM_017321393.1XP_017176882.1  probable G-protein coupled receptor 19 isoform X3

    UniProtKB/Swiss-Prot
    Q61121
    Conserved Domains (1) summary
    cd15008
    Location:61335
    7tmA_GPR19; G protein-coupled receptor 19, member of the class A family of seven-transmembrane G protein-coupled receptors
  9. XM_017321390.1XP_017176879.1  probable G-protein coupled receptor 19 isoform X1

    UniProtKB/TrEMBL
    A0A1N9MDH9
    Related
    ENSMUSP00000066287.7, OTTMUSP00000029040, ENSMUST00000066107.9, OTTMUST00000059663
    Conserved Domains (2) summary
    pfam00001
    Location:168416
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:158344
    7tm_4; Olfactory receptor

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001167693.1: Suppressed sequence

    Description
    NM_001167693.1: This RefSeq was permanently suppressed because a small upstream ORF with a strong Kozak signal overlaps the expected translation start site, making it unlikely that this transcript is translated.
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