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Gpr65 G-protein coupled receptor 65 [ Mus musculus (house mouse) ]

Gene ID: 14744, updated on 13-Dec-2022

Summary

Official Symbol
Gpr65provided by MGI
Official Full Name
G-protein coupled receptor 65provided by MGI
Primary source
MGI:MGI:108031
See related
Ensembl:ENSMUSG00000021886 AllianceGenome:MGI:108031
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dig1; TDAG8; Gpcr25
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; activation of GTPase activity; and positive regulation of Rho protein signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human GPR65 (G protein-coupled receptor 65). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thymus adult (RPKM 4.0), spleen adult (RPKM 4.0) and 21 other tissues See more
Orthologs
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Genomic context

See Gpr65 in Genome Data Viewer
Location:
12; 12 E
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (98234894..98242981)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (98268635..98276722)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 47415 Neighboring gene heterogeneous nuclear ribonucleoprotein A/B-like Neighboring gene galactosylceramidase Neighboring gene potassium channel, subfamily K, member 10 Neighboring gene predicted gene, 40893 Neighboring gene predicted gene, 25486

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
psychosine receptor
Names
G-protein coupled receptor 25
T-cell death-associated gene 8 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008152.3NP_032178.1  psychosine receptor

    See identical proteins and their annotated locations for NP_032178.1

    Status: VALIDATED

    Source sequence(s)
    AK134113, AK142853, BF453845
    Consensus CDS
    CCDS26096.1
    UniProtKB/Swiss-Prot
    Q61038
    UniProtKB/TrEMBL
    A0A0R4J0Y2, Q3UQ35, Q3UZ41
    Related
    ENSMUSP00000074581.5, ENSMUST00000075072.6
    Conserved Domains (1) summary
    pfam00001
    Location:68290
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    98234894..98242981
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)