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Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [ Mus musculus (house mouse) ]

Gene ID: 14699, updated on 18-Sep-2024

Summary

Official Symbol
Gngt1provided by MGI
Official Full Name
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1provided by MGI
Primary source
MGI:MGI:109165
See related
Ensembl:ENSMUSG00000029663 AllianceGenome:MGI:109165
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gng1; G(y)1; Hg3g1
Summary
Predicted to enable G-protein beta-subunit binding activity and GTPase activity. Acts upstream of or within eye photoreceptor cell development; phototransduction; and protein localization. Predicted to be located in photoreceptor inner segment and photoreceptor outer segment. Predicted to be part of heterotrimeric G-protein complex. Is expressed in brain; retina; retina outer nuclear layer; and spleen. Orthologous to human GNGT1 (G protein subunit gamma transducin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Gngt1 in Genome Data Viewer
Location:
6 A1; 6 1.81 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (3989082..3997441)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (3989082..3997436)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15005 Neighboring gene protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) pseudogene Neighboring gene STARR-seq mESC enhancer starr_15006 Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene guanine nucleotide binding protein (G protein), gamma 11 Neighboring gene RIKEN cDNA 4930528H21 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta-subunit binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of heterotrimeric G-protein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in photoreceptor inner segment IEA
Inferred from Electronic Annotation
more info
 
located_in photoreceptor inner segment ISO
Inferred from Sequence Orthology
more info
 
located_in photoreceptor outer segment IEA
Inferred from Electronic Annotation
more info
 
located_in photoreceptor outer segment ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein G(T) subunit gamma-T1
Names
guanine nucleotide binding protein (G protein), gamma 1 subunit
heterotrimeric guanine nucleotide-binding protein 3g1
transducin gamma chain

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010314.3NP_034444.1  guanine nucleotide-binding protein G(T) subunit gamma-T1

    See identical proteins and their annotated locations for NP_034444.1

    Status: VALIDATED

    Source sequence(s)
    AC022235, AK020903
    Consensus CDS
    CCDS39418.1
    UniProtKB/Swiss-Prot
    Q61012, Q9CR01
    Related
    ENSMUSP00000031673.6, ENSMUST00000031673.7
    Conserved Domains (1) summary
    smart00224
    Location:1274
    GGL; G protein gamma subunit-like motifs

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    3989082..3997441
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321388.3XP_017176877.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

    UniProtKB/Swiss-Prot
    Q61012, Q9CR01
    Conserved Domains (1) summary
    smart00224
    Location:1274
    GGL; G protein gamma subunit-like motifs
  2. XM_017321389.3XP_017176878.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

    UniProtKB/Swiss-Prot
    Q61012, Q9CR01
    Conserved Domains (1) summary
    smart00224
    Location:1274
    GGL; G protein gamma subunit-like motifs
  3. XM_006504986.3XP_006505049.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

    See identical proteins and their annotated locations for XP_006505049.1

    UniProtKB/Swiss-Prot
    Q61012, Q9CR01
    Conserved Domains (1) summary
    smart00224
    Location:1274
    GGL; G protein gamma subunit-like motifs