U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cas6 CRISPR-associated endoribonuclease Cas6 [ Pyrococcus furiosus DSM 3638 ]

Gene ID: 1469000, updated on 27-Nov-2025
Gene symbol
cas6
Gene description
CRISPR-associated endoribonuclease Cas6
Locus tag
PF_RS05680
Gene type
protein coding
Organism
Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PF1131
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_003413.1 (1081470..1082264, complement)

NC_003413.1Genomic Context describing neighboring genes Neighboring gene CRISPR-associated CARF protein Csx1 Neighboring gene type III-B CRISPR module-associated protein Cmr3 Neighboring gene type III-B CRISPR-associated protein Cas10/Cmr2 Neighboring gene type III-B CRISPR module RAMP protein Cmr1 Neighboring gene carbamoyltransferase family protein Neighboring gene hypothetical protein

Genomic Sequence:
NC_003413.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes. Carte J, et al. Genes Dev, 2008 Dec 15. PMID 19141480, Free PMC Article
  2. Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Robb FT, et al. Methods Enzymol, 2001. PMID 11210495
  3. Evidence of recent lateral gene transfer among hyperthermophilic archaea. Diruggiero J, et al. Mol Microbiol, 2000 Nov. PMID 11115105
  4. Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Maeder DL, et al. Genetics, 1999 Aug. PMID 10430560, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
CRISPR-associated endoribonuclease Cas6

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003413.1 Reference assembly

    Range
    1081470..1082264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011012271.1 CRISPR-associated endoribonuclease Cas6

    See identical proteins and their annotated locations for WP_011012271.1

    UniProtKB/Swiss-Prot
    Q8U1S4
    Conserved Domains (1) summary
    cd09759
    Location:1 → 237
    Cas6_I-A; CRISPR/Cas system-associated RAMP superfamily protein Cas6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8U1S4.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.