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cmr4 type III-B CRISPR module RAMP protein Cmr4 [ Pyrococcus furiosus DSM 3638 ]

Gene ID: 1468995, updated on 27-Nov-2025
Gene symbol
cmr4
Gene description
type III-B CRISPR module RAMP protein Cmr4
Locus tag
PF_RS05655
Gene type
protein coding
Organism
Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PF1126
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Try the new Transcripts and proteins table
Sequence:
NC_003413.1 (1074447..1075334, complement)

NC_003413.1Genomic Context describing neighboring genes Neighboring gene type I-B CRISPR-associated protein Cas7/Cst2/DevR Neighboring gene type I-B CRISPR-associated protein Cas8b1/Cst1 Neighboring gene type III-B CRISPR module RAMP protein Cmr6 Neighboring gene type III-B CRISPR module-associated protein Cmr5 Neighboring gene CRISPR-associated CARF protein Csx1 Neighboring gene type III-B CRISPR module-associated protein Cmr3 Neighboring gene type III-B CRISPR-associated protein Cas10/Cmr2 Neighboring gene type III-B CRISPR module RAMP protein Cmr1

Genomic Sequence:
NC_003413.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex. Ramia NF, et al. Cell Rep, 2014 Dec 11. PMID 25482566, Free PMC Article
  2. A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis. Makarova KS, et al. Nucleic Acids Res, 2002 Jan 15. PMID 11788711, Free PMC Article
  3. Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Robb FT, et al. Methods Enzymol, 2001. PMID 11210495
  4. Evidence of recent lateral gene transfer among hyperthermophilic archaea. Diruggiero J, et al. Mol Microbiol, 2000 Nov. PMID 11115105
  5. Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Maeder DL, et al. Genetics, 1999 Aug. PMID 10430560, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Four helically packed Cmr4 subunits make up the backbone of the Cmr complex.
    Title: Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex.
Submit: New GeneRIF Correction
Preferred Names
type III-B CRISPR module RAMP protein Cmr4

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003413.1 Reference assembly

    Range
    1074447..1075334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011012266.1 type III-B CRISPR module RAMP protein Cmr4

    See identical proteins and their annotated locations for WP_011012266.1

    UniProtKB/Swiss-Prot
    Q8U1S9
    UniProtKB/TrEMBL
    A0A5C0XQ24, I6U7E3
    Conserved Domains (1) summary
    TIGR02580
    Location:4 → 280
    cas_RAMP_Cmr4; CRISPR type III-B/RAMP module RAMP protein Cmr4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8U1S9.1

Gene LinkOut

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Other Literature Sources
Research Materials