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spt4 transcription elongation factor subunit Spt4 [ Pyrococcus furiosus DSM 3638 ]

Gene ID: 1468089, updated on 27-Nov-2025
Gene symbol
spt4
Gene description
transcription elongation factor subunit Spt4
Locus tag
PF_RS01290
Gene type
protein coding
Organism
Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PF0255
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Sequence:
NC_003413.1 (263306..263491, complement)

NC_003413.1Genomic Context describing neighboring genes Neighboring gene 30S ribosomal protein S27ae Neighboring gene 30S ribosomal protein S24e Neighboring gene GTP-dependent dephospho-CoA kinase Neighboring gene DNA-directed RNA polymerase Neighboring gene inorganic diphosphatase Neighboring gene deoxyribonuclease IV

Genomic Sequence:
NC_003413.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. RNA polymerase and transcription elongation factor Spt4/5 complex structure. Klein BJ, et al. Proc Natl Acad Sci U S A, 2011 Jan 11. PMID 21187417, Free PMC Article
  2. A global analysis of transcription reveals two modes of Spt4/5 recruitment to archaeal RNA polymerase. Smollett K, et al. Nat Microbiol, 2017 Mar 1. PMID 28248297, Free PMC Article
  3. Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity. Martinez-Rucobo FW, et al. EMBO J, 2011 Apr 6. PMID 21386817, Free PMC Article
  4. Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Robb FT, et al. Methods Enzymol, 2001. PMID 11210495
  5. Evidence of recent lateral gene transfer among hyperthermophilic archaea. Diruggiero J, et al. Mol Microbiol, 2000 Nov. PMID 11115105

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RNA polymerase and transcription elongation factor Spt4/5 complex structure
    Title: RNA polymerase and transcription elongation factor Spt4/5 complex structure.
Submit: New GeneRIF Correction
Preferred Names
transcription elongation factor subunit Spt4
WP_011011370.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003413.1 Reference assembly

    Range
    263306..263491 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011011370.1 transcription elongation factor subunit Spt4

    See identical proteins and their annotated locations for WP_011011370.1

    UniProtKB/Swiss-Prot
    Q8U440
    UniProtKB/TrEMBL
    A0A5C0XNG7, I6U5C4
    Conserved Domains (1) summary
    PRK08351
    Location:1 → 61
    PRK08351; DNA-directed RNA polymerase subunit E''; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8U440.1

Gene LinkOut

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