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Glud1 glutamate dehydrogenase 1 [ Mus musculus (house mouse) ]

Gene ID: 14661, updated on 7-Apr-2019

Summary

Official Symbol
Glud1provided by MGI
Official Full Name
glutamate dehydrogenase 1provided by MGI
Primary source
MGI:MGI:95753
See related
Ensembl:ENSMUSG00000021794
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Glud; Gdh-X; Gludl; AI118167
Expression
Ubiquitous expression in liver adult (RPKM 291.2), liver E18 (RPKM 185.4) and 27 other tissues See more
Orthologs

Genomic context

See Glud1 in Genome Data Viewer
Location:
14 B; 14 20.8 cM
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (34310727..34345033)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (35123913..35158219)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene synaptotagmin XV Neighboring gene shieldin complex subunit 2 Neighboring gene zinc finger, DHHC domain containing 17 pseudogene Neighboring gene B-cell CLL/lymphoma 7C pseudogene Neighboring gene family with sequence similarity 25, member C

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ADP binding ISO
Inferred from Sequence Orthology
more info
 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
GTP binding ISO
Inferred from Sequence Orthology
more info
 
NAD+ binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
glutamate dehydrogenase (NAD+) activity ISO
Inferred from Sequence Orthology
more info
 
glutamate dehydrogenase [NAD(P)+] activity IDA
Inferred from Direct Assay
more info
PubMed 
glutamate dehydrogenase [NAD(P)+] activity ISO
Inferred from Sequence Orthology
more info
 
leucine binding ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cellular amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
glutamate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
glutamate catabolic process ISO
Inferred from Sequence Orthology
more info
 
glutamine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of insulin secretion IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of insulin secretion ISO
Inferred from Sequence Orthology
more info
 
response to aluminum ion ISO
Inferred from Sequence Orthology
more info
 
tricarboxylic acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane HDA PubMed 
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion HDA PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glutamate dehydrogenase 1, mitochondrial
Names
GDH 1
NP_032159.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008133.4NP_032159.1  glutamate dehydrogenase 1, mitochondrial precursor

    See identical proteins and their annotated locations for NP_032159.1

    Status: VALIDATED

    Source sequence(s)
    AK089152, AK150637, AK161876
    Consensus CDS
    CCDS26935.1
    UniProtKB/Swiss-Prot
    P26443
    UniProtKB/TrEMBL
    Q3TSQ7
    Related
    ENSMUSP00000022322.9, ENSMUST00000022322.16
    Conserved Domains (1) summary
    COG0334
    Location:104546
    GdhA; Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    34310727..34345033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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