Format

Send to:

Choose Destination

DNAAF8 dynein axonemal assembly factor 8 [ Homo sapiens (human) ]

Gene ID: 146562, updated on 25-Jan-2022

Summary

Official Symbol
DNAAF8provided by HGNC
Official Full Name
dynein axonemal assembly factor 8provided by HGNC
Primary source
HGNC:HGNC:25081
See related
Ensembl:ENSG00000166246 AllianceGenome:HGNC:25081
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C16orf71
Summary
Predicted to enable dynein complex binding activity. Predicted to be involved in outer dynein arm assembly. Located in dynein axonemal particle. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Restricted expression toward testis (RPKM 29.4) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See DNAAF8 in Genome Data Viewer
Location:
16p13.3
Exon count:
12
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (4734344..4749396)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (4784538..4799397)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene mahogunin ring finger 1 Neighboring gene nudix hydrolase 16 like 1 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 3 Neighboring gene Sharpr-MPRA regulatory region 8628 Neighboring gene zinc finger protein 500 Neighboring gene septin 12 Neighboring gene small integral membrane protein 22 Neighboring gene rogdi atypical leucine zipper

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43261, DKFZp686H2240

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables dynein complex binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in outer dynein arm assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in dynein axonemal particle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in dynein axonemal particle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
dynein axonemal assembly factor 8
Names
dynein axonemal-associated protein 1
uncharacterized protein C16orf71

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139170.3NP_631909.2  dynein axonemal assembly factor 8

    See identical proteins and their annotated locations for NP_631909.2

    Status: VALIDATED

    Source sequence(s)
    BC035024, BI458862, BX648126
    Consensus CDS
    CCDS10521.1
    UniProtKB/Swiss-Prot
    Q8IYS4
    Related
    ENSP00000299320.4, ENST00000299320.10
    Conserved Domains (1) summary
    pfam15773
    Location:21520
    DUF4701; Domain of unknown function (DUF4701)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    4734344..4749396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017022976.1XP_016878465.1  dynein axonemal assembly factor 8 isoform X2

    UniProtKB/Swiss-Prot
    Q8IYS4
    Conserved Domains (1) summary
    pfam15773
    Location:21520
    DUF4701; Domain of unknown function (DUF4701)
  2. XM_005255144.3XP_005255201.1  dynein axonemal assembly factor 8 isoform X3

    Conserved Domains (1) summary
    pfam15773
    Location:1382
    DUF4701; Domain of unknown function (DUF4701)
  3. XM_017022975.1XP_016878464.1  dynein axonemal assembly factor 8 isoform X1

Support Center