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BICDL2 BICD family like cargo adaptor 2 [ Homo sapiens (human) ]

Gene ID: 146439, updated on 23-Nov-2021

Summary

Official Symbol
BICDL2provided by HGNC
Official Full Name
BICD family like cargo adaptor 2provided by HGNC
Primary source
HGNC:HGNC:33584
See related
Ensembl:ENSG00000162069 MIM:617003
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BICDR2; BICDR-2; CCDC64B
Expression
Broad expression in colon (RPKM 12.5), skin (RPKM 11.3) and 14 other tissues See more
Orthologs
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Genomic context

See BICDL2 in Genome Data Viewer
Location:
16p13.3
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (3027682..3036985, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3077683..3086945, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 12A Neighboring gene host cell factor C1 regulator 1 Neighboring gene THO complex 6 Neighboring gene uncharacterized LOC100128770 Neighboring gene matrix metallopeptidase 25 Neighboring gene MMP25 antisense RNA 1 Neighboring gene RNA, U1 small nuclear 125, pseudogene Neighboring gene interleukin 32

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC158069

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in Golgi to secretory granule transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BICD family-like cargo adapter 2
Names
BICD-related protein 2
bicaudal D-related protein 2
coiled-coil domain containing 64B
coiled-coil domain-containing protein 64B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103175.2NP_001096645.1  BICD family-like cargo adapter 2

    See identical proteins and their annotated locations for NP_001096645.1

    Status: VALIDATED

    Source sequence(s)
    AC108134
    Consensus CDS
    CCDS45393.1
    UniProtKB/Swiss-Prot
    A1A5D9
    Related
    ENSP00000373998.4, ENST00000389347.4
    Conserved Domains (2) summary
    COG1196
    Location:192450
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53296
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. NM_001369667.1NP_001356596.1  BICD family-like cargo adapter 2

    Status: VALIDATED

    Source sequence(s)
    AC108134
    Related
    ENSP00000459043.1, ENST00000572449.6
    Conserved Domains (2) summary
    COG1196
    Location:192450
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53296
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    3027682..3036985 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005255135.4XP_005255192.1  BICD family-like cargo adapter 2 isoform X1

    See identical proteins and their annotated locations for XP_005255192.1

    UniProtKB/Swiss-Prot
    A1A5D9
    Conserved Domains (2) summary
    COG1196
    Location:192450
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:53296
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_011522391.2XP_011520693.1  BICD family-like cargo adapter 2 isoform X2

    Conserved Domains (1) summary
    cl19219
    Location:118227
    DUF342; Protein of unknown function (DUF342)
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