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SLC22A31 solute carrier family 22 member 31 [ Homo sapiens (human) ]

Gene ID: 146429, updated on 23-Nov-2021

Summary

Official Symbol
SLC22A31provided by HGNC
Official Full Name
solute carrier family 22 member 31provided by HGNC
Primary source
HGNC:HGNC:27091
See related
Ensembl:ENSG00000259803
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in lung (RPKM 12.0), pancreas (RPKM 1.5) and 2 other tissues See more
Orthologs
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Genomic context

See SLC22A31 in Genome Data Viewer
Location:
16q24.3
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (89195756..89201678, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (89262169..89268086, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2138 Neighboring gene cadherin 15 Neighboring gene zinc finger protein 778 Neighboring gene Sharpr-MPRA regulatory region 4154 Neighboring gene uncharacterized LOC105371413

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative solute carrier family 22 member 31
Names
putative solute carrier family 22 member ENSG00000182157

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366322.1NP_001353251.1  putative solute carrier family 22 member 31 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC009113
  2. NM_001384763.1NP_001371692.1  putative solute carrier family 22 member 31 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AC009113
    Related
    ENSP00000508250.1, ENST00000682282.1
    Conserved Domains (1) summary
    cl28910
    Location:9383
    MFS; Major Facilitator Superfamily
  3. NM_001384764.1NP_001371693.1  putative solute carrier family 22 member 31 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:1316
    MFS; Major Facilitator Superfamily
  4. NM_001384765.1NP_001371694.1  putative solute carrier family 22 member 31 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC009113
    Conserved Domains (2) summary
    TIGR00898
    Location:4115
    2A0119; cation transport protein
    cl28910
    Location:1187
    MFS; Major Facilitator Superfamily
  5. NM_001384766.1NP_001371695.1  putative solute carrier family 22 member 31 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 6-8, encodes isoform e.
    Source sequence(s)
    AC009113
    Related
    ENSP00000474621.2, ENST00000562855.7
    Conserved Domains (1) summary
    cl28910
    Location:1275
    MFS; Major Facilitator Superfamily
  6. NM_001384767.1NP_001371696.1  putative solute carrier family 22 member 31 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 5, 7, and 8, encodes isoform e.
    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:1275
    MFS; Major Facilitator Superfamily
  7. NM_001384768.1NP_001371697.1  putative solute carrier family 22 member 31 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 5, 6, and 8, encodes isoform e.
    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:1275
    MFS; Major Facilitator Superfamily
  8. NM_001384769.1NP_001371698.1  putative solute carrier family 22 member 31 isoform e

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 5-7, encodes isoform e.
    Source sequence(s)
    AC009113
    Related
    ENSP00000481421.1, ENST00000614943.4
    Conserved Domains (1) summary
    cl28910
    Location:1275
    MFS; Major Facilitator Superfamily
  9. NM_001384770.1NP_001371699.1  putative solute carrier family 22 member 31 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:1239
    MFS; Major Facilitator Superfamily
  10. NM_001384771.1NP_001371700.1  putative solute carrier family 22 member 31 isoform g

    Status: VALIDATED

    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:1237
    MFS; Major Facilitator Superfamily
  11. NM_001384772.1NP_001371701.1  putative solute carrier family 22 member 31 isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 12 and 13, encodes isoform h.
    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:25181
    MFS; Major Facilitator Superfamily
  12. NM_001384773.1NP_001371702.1  putative solute carrier family 22 member 31 isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 11 and 13, encodes isoform h.
    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:25181
    MFS; Major Facilitator Superfamily
  13. NM_001384775.1NP_001371704.1  putative solute carrier family 22 member 31 isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13), as well as variants 11 and 12, encodes isoform h.
    Source sequence(s)
    AC009113
    Conserved Domains (1) summary
    cl28910
    Location:25181
    MFS; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    89195756..89201678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017022964.2XP_016878453.1  putative solute carrier family 22 member 31 isoform X3

    Conserved Domains (1) summary
    cl21472
    Location:178264
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  2. XM_017022965.1XP_016878454.1  putative solute carrier family 22 member 31 isoform X3

    Conserved Domains (1) summary
    cl21472
    Location:178264
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  3. XM_017022966.1XP_016878455.1  putative solute carrier family 22 member 31 isoform X3

    Conserved Domains (1) summary
    cl21472
    Location:178264
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  4. XM_017022963.1XP_016878452.1  putative solute carrier family 22 member 31 isoform X3

    Conserved Domains (1) summary
    cl21472
    Location:178264
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
  5. XM_017022962.1XP_016878451.1  putative solute carrier family 22 member 31 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001242757.1: Suppressed sequence

    Description
    NM_001242757.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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