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C16orf92 chromosome 16 open reading frame 92 [ Homo sapiens (human) ]

Gene ID: 146378, updated on 10-Oct-2020

Summary

Official Symbol
C16orf92provided by HGNC
Official Full Name
chromosome 16 open reading frame 92provided by HGNC
Primary source
HGNC:HGNC:26346
See related
Ensembl:ENSG00000167194 MIM:618911
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FIMP
Expression
Restricted expression toward testis (RPKM 8.5) See more
Orthologs

Genomic context

See C16orf92 in Genome Data Viewer
Location:
16p11.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (30023198..30027736)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (30034655..30036023)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene TAO kinase 2 Neighboring gene HIRA interacting protein 3 Neighboring gene INO80 complex subunit E Neighboring gene double C2 domain alpha Neighboring gene TLC domain containing 3B Neighboring gene uncharaterized LOC112694756 Neighboring gene aldolase, fructose-bisphosphate A Neighboring gene protein phosphatase 4 catalytic subunit

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Biological insights from 108 schizophrenia-associated genetic loci.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25404, MGC125422

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
fusion of sperm to egg plasma membrane involved in single fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
fertilization-influencing membrane protein; uncharacterized protein C16orf92

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109659.2NP_001103129.1  fertilization-influencing membrane protein isoform 1 precursor

    See identical proteins and their annotated locations for NP_001103129.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate splice acceptor site for exon 2; the N-terminus of the predicted protein is distinct compared to isoform 2.
    Source sequence(s)
    AC093512
    UniProtKB/Swiss-Prot
    Q96LL3
  2. NM_001109660.2NP_001103130.1  fertilization-influencing membrane protein isoform 2

    See identical proteins and their annotated locations for NP_001103130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice acceptor site for exon 2; the N-terminus of the predicted protein is distinct compared to isoform 1.
    Source sequence(s)
    AC093512
    Consensus CDS
    CCDS42146.1
    UniProtKB/Swiss-Prot
    Q96LL3
    Related
    ENSP00000300575.2, ENST00000300575.6
  3. NM_001353379.2NP_001340308.1  fertilization-influencing membrane protein isoform 3 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a longer and distinct C-terminus compared to isoform 1. This variant encodes the longest isoform (3).
    Source sequence(s)
    AC093512

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    30023198..30027736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450162.1XP_024305930.1  uncharacterized protein C16orf92 isoform X2

  2. XM_024450161.1XP_024305929.1  uncharacterized protein C16orf92 isoform X1

RNA

  1. XR_002957776.1 RNA Sequence

  2. XR_002957778.1 RNA Sequence

  3. XR_002957779.1 RNA Sequence

  4. XR_002957777.1 RNA Sequence

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