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Gk2 glycerol kinase 2 [ Mus musculus (house mouse) ]

Gene ID: 14626, updated on 5-Jan-2023

Summary

Official Symbol
Gk2provided by MGI
Official Full Name
glycerol kinase 2provided by MGI
Primary source
MGI:MGI:1329027
See related
Ensembl:ENSMUSG00000050553 AllianceGenome:MGI:1329027
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GKTA; Gk-rs2
Summary
Predicted to enable glycerol kinase activity. Predicted to be involved in several processes, including glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in mitochondrion. Orthologous to human GK2 (glycerol kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Gk2 in Genome Data Viewer
Location:
5 E3; 5 47.71 cM
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (97602989..97604882, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (97455130..97457023, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33969 Neighboring gene RIKEN cDNA 4930467D21 gene Neighboring gene N(alpha)-acetyltransferase 11, NatA catalytic subunit Neighboring gene predicted gene, 34029 Neighboring gene predicted gene, 54318

Genomic regions, transcripts, and products

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables glycerol kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in flagellated sperm motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in glycerol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycerol-3-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycerol-3-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in sperm mitochondrial sheath assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in triglyceride metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in sperm midpiece ISO
Inferred from Sequence Orthology
more info
 
located_in sperm mitochondrial sheath IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
glycerol kinase 2
Names
ATP:glycerol 3-phosphotransferase 2
GK 2
glucokinase activity, related sequence 2
glycerokinase 2
glycerol kinase, testis specific 2
NP_034424.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010294.2NP_034424.1  glycerol kinase 2

    See identical proteins and their annotated locations for NP_034424.1

    Status: VALIDATED

    Source sequence(s)
    AC122875, BC050764, BC061147
    Consensus CDS
    CCDS19454.1
    UniProtKB/Swiss-Prot
    Q9WU65
    Related
    ENSMUSP00000052226.3, ENSMUST00000059657.4
    Conserved Domains (2) summary
    cd07792
    Location:11513
    FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
    TIGR01311
    Location:11513
    glycerol_kin; glycerol kinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    97602989..97604882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)