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Gjb5 gap junction protein, beta 5 [ Mus musculus (house mouse) ]

Gene ID: 14622, updated on 18-Sep-2018

Summary

Official Symbol
Gjb5provided by MGI
Official Full Name
gap junction protein, beta 5provided by MGI
Primary source
MGI:MGI:95723
See related
Ensembl:ENSMUSG00000042357 Vega:OTTMUSG00000009375
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gjb-5; Cx31.1; Cnx31.1
Expression
Biased expression in placenta adult (RPKM 18.0), colon adult (RPKM 3.2) and 4 other tissues See more
Orthologs

Genomic context

See Gjb5 in Genome Data Viewer
Location:
4 D2.2; 4 61.51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (127354809..127358164, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (127032053..127035408, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40251 Neighboring gene gap junction protein, beta 3 Neighboring gene gap junction protein, beta 4 Neighboring gene predicted gene 12947 Neighboring gene predicted gene, 40252

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

  • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
    Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
cell communication IEA
Inferred from Electronic Annotation
more info
 
labyrinthine layer morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
spongiotrophoblast differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
trophoblast giant cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell junction IEA
Inferred from Electronic Annotation
more info
 
connexin complex IEA
Inferred from Electronic Annotation
more info
 
gap junction IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
gap junction beta-5 protein
Names
connexin-31.1
gap junction membrane channel protein beta 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010291.3NP_034421.1  gap junction beta-5 protein

    See identical proteins and their annotated locations for NP_034421.1

    Status: PROVISIONAL

    Source sequence(s)
    AK082917
    Consensus CDS
    CCDS18670.1
    UniProtKB/Swiss-Prot
    Q02739
    UniProtKB/TrEMBL
    Q542M8
    Related
    ENSMUSP00000045325.2, OTTMUSP00000009765, ENSMUST00000046498.2, OTTMUST00000021352
    Conserved Domains (3) summary
    smart00037
    Location:4275
    CNX; Connexin homologues
    smart01089
    Location:139206
    Connexin_CCC; Gap junction channel protein cysteine-rich domain
    pfam00029
    Location:2208
    Connexin; Connexin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    127354809..127358164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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