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PIERCE2 piercer of microtubule wall 2 [ Homo sapiens (human) ]

Gene ID: 145788, updated on 28-May-2022

Summary

Official Symbol
PIERCE2provided by HGNC
Official Full Name
piercer of microtubule wall 2provided by HGNC
Primary source
HGNC:HGNC:44654
See related
Ensembl:ENSG00000261652 MIM:619669; AllianceGenome:HGNC:44654
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf65; C15orf65
Expression
Broad expression in testis (RPKM 4.6), thyroid (RPKM 2.3) and 23 other tissues See more
Orthologs
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Genomic context

See PIERCE2 in Genome Data Viewer
Location:
15q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (55408495..55418798)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (53211727..53222035)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (55700693..55710996)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene DNAAF4-CCPG1 readthrough (NMD candidate) Neighboring gene cell cycle progression 1 Neighboring gene microRNA 628 Neighboring gene Sharpr-MPRA regulatory region 6559 Neighboring gene dynein axonemal assembly factor 4 Neighboring gene thioesterase superfamily member 4 pseudogene Neighboring gene uncharacterized mitochondrial protein AtMg00860-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ27352, DKFZp686K1763

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in axoneme assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cilium movement ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in determination of left/right symmetry ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in axonemal microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
piercer of microtubule wall 2 protein
Names
uncharacterized protein C15orf65

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198784.2NP_001185713.1  piercer of microtubule wall 2 protein

    See identical proteins and their annotated locations for NP_001185713.1

    Status: VALIDATED

    Source sequence(s)
    AC013355, AK130862, AV735277, BX648577
    Consensus CDS
    CCDS58363.1
    UniProtKB/Swiss-Prot
    H3BRN8
    Related
    ENSP00000456337.1, ENST00000569691.2
    Conserved Domains (1) summary
    pfam14892
    Location:58109
    DUF4490; Domain of unknown function (DUF4490)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    55408495..55418798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    53211727..53222035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)