Sign in to NCBI
Format

Send to:

Choose Destination

pcn DNA polymerase III sliding clamp [ Sulfolobus solfataricus P2 ]

Gene ID: 1455544, updated on 19-Sep-2017

Summary

Go to the top of the page Help
Gene symbol
pcn
Gene description
DNA polymerase III sliding clamp
Locus tag
SSO_RS02035
Gene type
protein coding
Organism
Sulfolobus solfataricus P2 (strain: P2)
Lineage
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus
Old locus tag
SSO0405

Genomic context

Go to the top of the page Help
Sequence:
NC_002754.1 (355009..355788)

NC_002754.1Genomic Context describing neighboring genes Neighboring gene riboflavin synthase Neighboring gene 3,4-dihydroxy-2-butanone-4-phosphate synthase Neighboring gene DUF2208 domain-containing protein Neighboring gene cobyrinic acid a,c-diamide synthase Neighboring gene 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Neighboring gene methionine synthase Neighboring gene 30S ribosomal protein S15 Neighboring gene sirohydrochlorin cobaltochelatase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_002754.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod-shaped virus 2. Gardner AF, et al. J Virol, 2014 Jun. PMID 24696494, Free PMC Article
  2. Two DNA polymerase sliding clamps from the thermophilic archaeon Sulfolobus solfataricus. De Felice M, et al. J Mol Biol, 1999 Aug 6. PMID 10438605
  3. The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus. Cannone G, et al. Biochem J, 2015 Jan 15. PMID 25299633
  4. Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Xing G, et al. Mol Microbiol, 2009 Feb. PMID 19054331
  5. A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Pascal JM, et al. Mol Cell, 2006 Oct 20. PMID 17052461

See all (6) citations in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  1. The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus.
    Title: The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus.
  2. Sulfolobus islandicus rod-shaped virus 2 proteins P83a/b, P84c, P119a and P121 were found to interact with SsoPCNA3.
    Title: Protein-protein interactions leading to recruitment of the host DNA sliding clamp by the hyperthermophilic Sulfolobus islandicus rod-shaped virus 2.
  3. Dpo4 binds via its C-terminal PIP-box to the conserved PIP binding site of PCNA1.
    Title: Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA.
Submit: New GeneRIF Correction

Pathways from BioSystems

Go to the top of the page Help
  • Base excision repair, organism-specific biosystem (from KEGG)
    Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
  • Base excision repair, conserved biosystem (from KEGG)
    Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
  • DNA replication, organism-specific biosystem (from KEGG)
    DNA replication, organism-specific biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
  • DNA replication, conserved biosystem (from KEGG)
    DNA replication, conserved biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
  • Mismatch repair, organism-specific biosystem (from KEGG)
    Mismatch repair, organism-specific biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
  • Mismatch repair, conserved biosystem (from KEGG)
    Mismatch repair, conserved biosystemDNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preven...
  • Nucleotide excision repair, organism-specific biosystem (from KEGG)
    Nucleotide excision repair, organism-specific biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...
  • Nucleotide excision repair, conserved biosystem (from KEGG)
    Nucleotide excision repair, conserved biosystemNucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the ...

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Names
DNA polymerase III sliding clamp

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002754.1 Reference assembly

    Range
    355009..355788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_009988781.1 DNA polymerase III sliding clamp [Sulfolobus solfataricus]

    See identical proteins and their annotated locations for WP_009988781.1

    UniProtKB/TrEMBL
    A0A0E3K8Y2, D0KS98
    Conserved Domains (2) summary
    PRK01115
    Location:16 → 259
    PRK01115; DNA polymerase sliding clamp; Validated
    cd00577
    Location:19 → 259
    PCNA; Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea. These polymerase processivity factors play a role in DNA replication and repair. PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
You are here: NCBI > Genes & Expression > Gene
Support Center