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CSNK1G2 casein kinase 1 gamma 2 [ Homo sapiens (human) ]

Gene ID: 1455, updated on 7-Jun-2020

Summary

Official Symbol
CSNK1G2provided by HGNC
Official Full Name
casein kinase 1 gamma 2provided by HGNC
Primary source
HGNC:HGNC:2455
See related
Ensembl:ENSG00000133275 MIM:602214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CK1g2
Expression
Broad expression in testis (RPKM 21.2), spleen (RPKM 15.0) and 25 other tissues See more
Orthologs

Genomic context

See CSNK1G2 in Genome Data Viewer
Location:
19p13.3
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (1941149..1981338)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (1941148..1981337)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 4 Neighboring gene adenosine deaminase tRNA specific 3 Neighboring gene uncharacterized LOC105372238 Neighboring gene CSNK1G2 antisense RNA 1 Neighboring gene BTB domain containing 2 Neighboring gene uncharacterized LOC107985278

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-serine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation TAS
Traceable Author Statement
more info
PubMed 
signal transduction TAS
Traceable Author Statement
more info
PubMed 
sphingolipid biosynthetic process TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
membrane HDA PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
casein kinase I isoform gamma-2; casein kinase I
Names
CKI-gamma 2
casein kinase 1 isoform gamma-2
NP_001310.3
XP_005259555.1
XP_005259556.1
XP_005259557.1
XP_005259558.1
XP_016881786.1
XP_016881787.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319.7NP_001310.3  casein kinase I isoform gamma-2

    See identical proteins and their annotated locations for NP_001310.3

    Status: VALIDATED

    Source sequence(s)
    AC005306, AC012615
    Consensus CDS
    CCDS12077.1
    UniProtKB/Swiss-Prot
    P78368
    Related
    ENSP00000255641.7, ENST00000255641.13
    Conserved Domains (1) summary
    cd14126
    Location:45332
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    1941149..1981338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005259498.1XP_005259555.1  casein kinase I isoform X1

    See identical proteins and their annotated locations for XP_005259555.1

    Conserved Domains (2) summary
    COG0515
    Location:45398
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45362
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
  2. XM_005259500.1XP_005259557.1  casein kinase I isoform X2

    Conserved Domains (3) summary
    COG0515
    Location:45393
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45332
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:332399
    CK1gamma_C; Casein kinase 1 gamma C terminal
  3. XM_017026297.1XP_016881786.1  casein kinase I isoform X1

    Conserved Domains (2) summary
    COG0515
    Location:45398
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45362
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
  4. XM_005259499.3XP_005259556.1  casein kinase I isoform X1

    See identical proteins and their annotated locations for XP_005259556.1

    Conserved Domains (2) summary
    COG0515
    Location:45398
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:45362
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
  5. XM_005259501.2XP_005259558.1  casein kinase I isoform X3

    Conserved Domains (3) summary
    COG0515
    Location:21345
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14126
    Location:15284
    STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
    pfam12605
    Location:284351
    CK1gamma_C; Casein kinase 1 gamma C terminal
  6. XM_017026298.1XP_016881787.1  casein kinase I isoform X4

RNA

  1. XR_430129.1 RNA Sequence

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