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PPP1R36 protein phosphatase 1 regulatory subunit 36 [ Homo sapiens (human) ]

Gene ID: 145376, updated on 24-Nov-2020

Summary

Official Symbol
PPP1R36provided by HGNC
Official Full Name
protein phosphatase 1 regulatory subunit 36provided by HGNC
Primary source
HGNC:HGNC:20097
See related
Ensembl:ENSG00000165807
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C14orf50
Expression
Biased expression in testis (RPKM 17.6), stomach (RPKM 2.2) and 4 other tissues See more
Orthologs

Genomic context

See PPP1R36 in Genome Data Viewer
Location:
14q23.3
Exon count:
14
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (64549896..64589386)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (65016620..65056099)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 25 Neighboring gene uncharacterized LOC102723809 Neighboring gene zinc finger and BTB domain containing 1 Neighboring gene heat shock protein family A (Hsp70) member 2 Neighboring gene nucleoporin 50 pseudogene 1 Neighboring gene pleckstrin homology and RhoGEF domain containing G3 Neighboring gene spectrin beta, erythrocytic

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
phosphatase binding IEA
Inferred from Electronic Annotation
more info
 
protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 36

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172365.3NP_758953.1  protein phosphatase 1 regulatory subunit 36

    See identical proteins and their annotated locations for NP_758953.1

    Status: VALIDATED

    Source sequence(s)
    AL049869, BC068989
    Consensus CDS
    CCDS9767.1
    UniProtKB/Swiss-Prot
    Q96LQ0
    Related
    ENSP00000298705.1, ENST00000298705.6
    Conserved Domains (1) summary
    pfam14895
    Location:79412
    PPPI_inhib; Protein phosphatase 1 inhibitor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    64549896..64589386
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005267355.4XP_005267412.1  protein phosphatase 1 regulatory subunit 36 isoform X2

    Conserved Domains (1) summary
    pfam14895
    Location:35368
    PPPI_inhib; Protein phosphatase 1 inhibitor
  2. XM_024449485.1XP_024305253.1  protein phosphatase 1 regulatory subunit 36 isoform X4

    Conserved Domains (1) summary
    pfam14895
    Location:1234
    PPPI_inhib; Protein phosphatase 1 inhibitor
  3. XM_011536468.3XP_011534770.1  protein phosphatase 1 regulatory subunit 36 isoform X3

    Conserved Domains (1) summary
    pfam14895
    Location:79367
    PPPI_inhib; Protein phosphatase 1 inhibitor
  4. XM_005267354.4XP_005267411.1  protein phosphatase 1 regulatory subunit 36 isoform X1

    Conserved Domains (1) summary
    pfam14895
    Location:67400
    PPPI_inhib; Protein phosphatase 1 inhibitor
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