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lptM LptD oxidative maturation-associated lipoprotein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 1450304, updated on 6-Jul-2026
Official Symbol
lptM
Official Full Name
LptD oxidative maturation-associated lipoprotein
Primary source
ECOCYC:G0-10471
Locus tag
b4558
See related
ASAP:ABE-0285079
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3803; yifL
Summary
First 19 aa are predicted to be a type II signal peptide. [More information is available at EcoGene: EG12353].
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Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (3994522..3994725)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene adenylate cyclase Neighboring gene frataxin CyaY Neighboring gene protein YzcX Neighboring gene diaminopimelate epimerase Neighboring gene DUF484 domain-containing protein YigA Neighboring gene site-specific tyrosine recombinase Neighboring gene 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Intrinsic and extrinsic approaches for detecting genes in a bacterial genome. Borodovsky M, et al. Nucleic Acids Res, 1994 Nov 11. PMID 7984428, Free PMC Article
  2. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Daniels DL, et al. Science, 1992 Aug 7. PMID 1379743
  3. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
  4. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130
  5. LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry. Yang Y, et al. Nat Commun, 2023 Oct 11. PMID 37821449, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Gram-negative-bacterium-type cell outer membrane assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
LptD oxidative maturation-associated lipoprotein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3994522..3994725
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_588473.1 LptD oxidative maturation-associated lipoprotein

    See identical proteins and their annotated locations for YP_588473.1

    Status: REVIEWED

    Conserved Domains (1) summary
    COG5567
    Location:1 → 63
    YifL; Predicted small periplasmic lipoprotein YifL (function unknown0 [Function unknown]
Nucleotide Protein
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