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VNG_RS01375 DNA topoisomerase I [ Halobacterium salinarum NRC-1 ]

Gene ID: 1449018, updated on 30-Jan-2018

Summary

Gene symbol
VNG_RS01375
Gene description
DNA topoisomerase I
Locus tag
VNG_RS01375
Gene type
protein coding
Organism
Halobacterium salinarum NRC-1 (strain: NRC-1; ATCC 700922, culture-collection: ATCC:700922, old-name: Halobacterium sp. NRC-1)
Lineage
Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium
Old locus tag
VNG0349G; VNG0349Gm

Genomic context

Sequence:
NC_002607.1 (275494..277983)

NC_002607.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General protein information

Names
DNA topoisomerase I
WP_010902213.1
  • catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002607.1 Reference assembly

    Range
    275494..277983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010902213.1 Peptide Sequence

    See identical proteins and their annotated locations for WP_010902213.1

    UniProtKB/TrEMBL
    B0R363
    Conserved Domains (5) summary
    cd03362
    Location:1147
    TOPRIM_TopoIA_TopoIII; TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving ...
    PRK07219
    Location:1820
    PRK07219; DNA topoisomerase I; Validated
    cd00186
    Location:152573
    TOP1Ac; DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA ...
    pfam01396
    Location:600635
    zf-C4_Topoisom; Topoisomerase DNA binding C4 zinc finger
    pfam14520
    Location:776828
    HHH_5; Helix-hairpin-helix domain
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