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Nipsnap2 nipsnap homolog 2 [ Mus musculus (house mouse) ]

Gene ID: 14467, updated on 30-Apr-2024

Summary

Official Symbol
Nipsnap2provided by MGI
Official Full Name
nipsnap homolog 2provided by MGI
Primary source
MGI:MGI:1278343
See related
Ensembl:ENSMUSG00000029432 AllianceGenome:MGI:1278343
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gbas
Summary
Involved in positive regulation of high voltage-gated calcium channel activity. Located in cytoplasm. Is expressed in olfactory cortex ventricular layer; rest of cerebellum ventricular layer; and telencephalon ventricular layer. Orthologous to human NIPSNAP2 (nipsnap homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 142.2), cerebellum adult (RPKM 27.2) and 21 other tissues See more
Orthologs
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Genomic context

See Nipsnap2 in Genome Data Viewer
Location:
5 G1.3; 5 68.26 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (129802080..129835391)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (129725016..129758327)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene septin 14 Neighboring gene STARR-seq mESC enhancer starr_14455 Neighboring gene STARR-positive B cell enhancer ABC_E11303 Neighboring gene mitochondrial ribosomal protein S17 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:130230774-130230883 Neighboring gene STARR-seq mESC enhancer starr_14458 Neighboring gene STARR-seq mESC enhancer starr_14459 Neighboring gene phosphoserine phosphatase Neighboring gene STARR-positive B cell enhancer ABC_E854 Neighboring gene predicted gene, 23245 Neighboring gene chaperonin containing TCP1 subunit 6A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in mitochondrion organization ISO
Inferred from Sequence Orthology
more info
 
involved_in oxidative phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of high voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein NipSnap homolog 2
Names
glioblastoma amplified sequence

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008095.5NP_032121.3  protein NipSnap homolog 2

    See identical proteins and their annotated locations for NP_032121.3

    Status: VALIDATED

    Source sequence(s)
    AC120413, AC186296
    Consensus CDS
    CCDS19698.1
    UniProtKB/TrEMBL
    Q3TD78, Q7TMG8
    Related
    ENSMUSP00000083211.4, ENSMUST00000086046.10
    Conserved Domains (1) summary
    pfam07978
    Location:182279
    NIPSNAP; NIPSNAP

RNA

  1. NR_185194.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC120413, AC186296

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    129802080..129835391
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_377054.4 RNA Sequence

  2. XR_377052.4 RNA Sequence