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thiM hydroxyethylthiazole kinase [ Pyrococcus horikoshii OT3 ]

Gene ID: 1443477, updated on 16-Jun-2026
Gene symbol
thiM
Gene description
hydroxyethylthiazole kinase
Locus tag
PH_RS05430
Gene type
protein coding
Organism
Pyrococcus horikoshii OT3 (strain: OT3, type-material: type strain of Pyrococcus horikoshii)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PH1157
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Sequence:
NC_000961.1 (1050616..1051413, complement)

NC_000961.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene M20/M25/M40 family metallo-hydrolase Neighboring gene bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Neighboring gene thiamine phosphate synthase Neighboring gene putative hydroxymethylpyrimidine transporter CytX Neighboring gene TenA family protein Neighboring gene thiaminase II Neighboring gene NCS2 family permease Neighboring gene metal-dependent transcriptional regulator

Genomic Sequence:
NC_000961.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. Campobasso N, et al. Biochemistry, 2000 Jul 11. PMID 10891066
  2. Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections. Drebes J, et al. Sci Rep, 2016 Mar 10. PMID 26960569, Free PMC Article
  3. Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3. Kawarabayasi Y, et al. DNA Res, 1998 Apr 30. PMID 9679194

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
hydroxyethylthiazole kinase
WP_010885242.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000961.1 Reference assembly

    Range
    1050616..1051413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010885242.1 hydroxyethylthiazole kinase

    See identical proteins and their annotated locations for WP_010885242.1

    UniProtKB/Swiss-Prot
    O58877
    Conserved Domains (1) summary
    PRK09355
    Location:3 → 263
    PRK09355; hydroxyethylthiazole kinase; Validated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O58877.1

Gene LinkOut

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