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FREY1 Frey regulator of sperm-oocyte fusion 1 [ Homo sapiens (human) ]

Gene ID: 143678, updated on 27-Sep-2022

Summary

Official Symbol
FREY1provided by HGNC
Official Full Name
Frey regulator of sperm-oocyte fusion 1provided by HGNC
Primary source
HGNC:HGNC:37213
See related
Ensembl:ENSG00000234776 AllianceGenome:HGNC:37213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Frey; C11orf94
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 6.7) and kidney (RPKM 3.4) See more
Orthologs
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Genomic context

See FREY1 in Genome Data Viewer
Location:
11p11.2
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (45906534..45907271, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (46062464..46063201, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (45928085..45928822, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 8 interacting protein 1 Neighboring gene uncharacterized LOC124902668 Neighboring gene Sharpr-MPRA regulatory region 10000 Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene LARGE xylosyl- and glucuronyltransferase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in fusion of sperm to egg plasma membrane involved in single fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in maintenance of protein localization in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in sperm-egg recognition ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein C11orf94

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080446.3NP_001073915.2  uncharacterized protein C11orf94 precursor

    See identical proteins and their annotated locations for NP_001073915.2

    Status: VALIDATED

    Source sequence(s)
    AC068385
    Consensus CDS
    CCDS44577.1
    UniProtKB/Swiss-Prot
    C9JXX5
    Related
    ENSP00000401498.1, ENST00000449465.2
    Conserved Domains (1) summary
    pfam15878
    Location:496
    DUF4733; Domain of unknown function (DUF4733)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    45906534..45907271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    46062464..46063201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)