Format

Send to:

Choose Destination

OR51E1 olfactory receptor family 51 subfamily E member 1 [ Homo sapiens (human) ]

Gene ID: 143503, updated on 23-Nov-2021

Summary

Official Symbol
OR51E1provided by HGNC
Official Full Name
olfactory receptor family 51 subfamily E member 1provided by HGNC
Primary source
HGNC:HGNC:15194
See related
Ensembl:ENSG00000180785 MIM:611267
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
POGR; DGPCR; PSGR2; D-GPCR; GPR136; GPR164; OR51E1P; OR52A3P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Biased expression in prostate (RPKM 7.2), fat (RPKM 4.9) and 8 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR51E1 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (4643982..4655488)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (4665212..4676718)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 68 Neighboring gene olfactory receptor family 51 subfamily D member 1 Neighboring gene CRISPRi-validated cis-regulatory element chr11.762 Neighboring gene olfactory receptor family 51 subfamily A member 9 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13581, MGC24137

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 51E1
Names
Dresden-G-protein-coupled receptor
G-protein coupled receptor 164
olfactory receptor 52A3
olfactory receptor OR11-15
olfactory receptor, family 51, subfamily E, member 1 pseudogene
olfactory receptor, family 52, subfamily A, member 3 pseudogene
prostate overexpressed G protein-coupled receptor
prostate-specific G protein-coupled receptor 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152430.4NP_689643.2  olfactory receptor 51E1

    See identical proteins and their annotated locations for NP_689643.2

    Status: VALIDATED

    Source sequence(s)
    AC090719, AL833127, BC022401
    Consensus CDS
    CCDS31358.2
    UniProtKB/Swiss-Prot
    Q8TCB6
    UniProtKB/TrEMBL
    A0A126GVF8
    Related
    ENSP00000380155.5, ENST00000396952.6
    Conserved Domains (2) summary
    pfam00001
    Location:44294
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:34309
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    4643982..4655488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center