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Fut9 fucosyltransferase 9 [ Mus musculus (house mouse) ]

Gene ID: 14348, updated on 18-Oct-2022

Summary

Official Symbol
Fut9provided by MGI
Official Full Name
fucosyltransferase 9provided by MGI
Primary source
MGI:MGI:1330859
See related
Ensembl:ENSMUSG00000055373 AllianceGenome:MGI:1330859
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mFUT9; mFuc-TIX
Summary
Enables 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in cellular polysaccharide biosynthetic process and fucosylation. Acts upstream of or within protein glycosylation. Located in Golgi apparatus. Is expressed in brain; central nervous system; and telencephalon. Orthologous to human FUT9 (fucosyltransferase 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 6.6), cerebellum adult (RPKM 5.7) and 7 other tissues See more
Orthologs
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Genomic context

See Fut9 in Genome Data Viewer
Location:
4 A3; 4 10.59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (25609333..25800003, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (25609333..25800003, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11893 Neighboring gene predicted gene, 24977 Neighboring gene predicted gene, 24042 Neighboring gene predicted gene, 42263

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in N-glycan fucosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular polysaccharide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in fucosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in fucosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in glycosphingolipid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in oligosaccharide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein O-linked glycosylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein glycosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of leukocyte cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of leukocyte tethering or rolling ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 
located_in trans-Golgi network membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9
Names
alpha-(1,3)-fucosyltransferase 9
fuc-TIX
fucT-IX
fucosyltransferase IX
galactoside 3-L-fucosyltransferase
NP_034373.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010243.3NP_034373.1  4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9

    See identical proteins and their annotated locations for NP_034373.1

    Status: VALIDATED

    Source sequence(s)
    AL935336, BB626126, BX323863
    Consensus CDS
    CCDS18011.1
    UniProtKB/Swiss-Prot
    O88819, Q3TQ63
    UniProtKB/TrEMBL
    Q14AE3
    Related
    ENSMUSP00000081826.5, ENSMUST00000084770.5
    Conserved Domains (2) summary
    pfam00852
    Location:185354
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:62169
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    25609333..25800003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)